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Diabetic Foot clinical trials

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NCT ID: NCT02838784 Recruiting - Clinical trials for Foot Ulcer, Diabetic

Efficacy and Safety of Artacent™ for Treatment Resistant Lower Extremity Venous and Diabetic Ulcers

TMArtacent
Start date: September 2016
Phase: N/A
Study type: Interventional

This study will compare the proportion of patients who have wound closure within 12 weeks as well as the time to wound closure in patients receiving Artacent™ versus standard of care for treatment of non-healing lower extremity wounds. The recurrence of healed wounds will be assessed at 6 months via a telephone survey

NCT ID: NCT02834858 Recruiting - Diabetic Foot Clinical Trials

Umbilical Cord Mesenchymal Stem Cells Infusion for Diabetes Related Vascular Complications

Start date: January 2016
Phase: Phase 1
Study type: Interventional

Stem cell therapy has been a new and effective therapy in recent years for diabetic foot.This study intends to establish an optimal clinical research program, and attempts to break the technical bottleneck in the stem cell therapy for treating diabetes related vascular complications.

NCT ID: NCT02831075 Recruiting - Diabetic Foot Clinical Trials

A Clinical Study Using Adipose-derived Stem Cells for Diabetic Foot

Start date: January 2015
Phase: Phase 1
Study type: Interventional

Stem cell therapy has been a new and effective therapy in recent years for diabetic foot.This study intends to establish an optimal clinical research program, and attempts to break the technical bottleneck in the stem cell therapy for treating diabetes related vascular complications.

NCT ID: NCT02818322 Recruiting - Clinical trials for Diabetic Foot - Telemedical Monitoring

The Role of Telemedical Monitoring in Diabetic Foot Ulcer Care

A15-06
Start date: April 2016
Phase: N/A
Study type: Interventional

The role of telemedical monitoring in diabetic foot care is still uncertain. The aim is to compare telemedical + standard and standard alone outpatient monitoring in the care of patients with diabetic foot ulcers in a randomized controlled trial. The primary outcome of the overall study is the time of ulcer healing. The number of amputation, hospital admissions and surgical procedure will be also reported. Investigators hope to include 150 patients in this study.

NCT ID: NCT02816749 Recruiting - Clinical trials for Diabetic Foot Ulcers

Maggot Debridement Therapy Versus Conventional Dressing Therapy to Treat Diabetic Foot Ulcers

MDTDF
Start date: June 2016
Phase: Phase 4
Study type: Interventional

This is a prospective study of participants with diabetic foot ulcers who will receive either maggot debridement therapy (MDT) or conventional dressing therapy (CDT). Wound healing time is the main outcome measure to compare the clinical efficacy of these two therapies. The investigators developed a hypothesis that MDT could achieve remarkable shorter time and better healing rate for wound closure when compared with CDT.

NCT ID: NCT02813161 Recruiting - Clinical trials for Quality of Patient Care

The Diabetic Foot Ulcer Registry

DFUR
Start date: February 2015
Phase:
Study type: Observational [Patient Registry]

This is an observational, longitudinal real world registry of diabetic foot ulcers created from electronic health record data obtained in the course of clinical care. Data from certified electronic health records transmit data as part of the requirement to share data with a specialty registry under Objective 10 of Meaningful Use of an EHR.

NCT ID: NCT02796079 Recruiting - Diabetic Foot Clinical Trials

A Clinical Study Using Autologous Bone Marrow Stem Cell for Diabetes Related Vascular Complications

Start date: January 2015
Phase: Phase 1
Study type: Interventional

Stem cell therapy has been a new and effective therapy in recent years for diabetic foot.This study intends to establish an optimal clinical research program, and attempts to break the technical bottleneck in the stem cell therapy for treating diabetes related vascular complications.

NCT ID: NCT02742233 Recruiting - Diabetic Foot Ulcer Clinical Trials

Dipeptidyl Peptidase 4 Inhibition Facilitate Healing of Diabetic Ulcers

DPP4i
Start date: November 2015
Phase: Phase 4
Study type: Interventional

To investigate the effect of Dipeptidyl Peptidase 4 Inhibition on wound healing in patients with diabetic foot ulcers, the investigators randomly divided the participants into two groups: saxagliptin with regular treatment group,placebo with regular treatment group. The clinical data are collected at the given time point. This study aimed to observe the potential protective effect of DPP4i on diabetic ulcers.

NCT ID: NCT02666131 Recruiting - Clinical trials for Diabetic Foot Ulcers

A Study of Granexin Gel to Treat Diabetic Foot Ulcer

Start date: July 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether Granexin gel is safe and effective in the treatment of diabetic foot ulcers.

NCT ID: NCT02565940 Recruiting - Clinical trials for Diabetic Foot Infection

Study by Metagenomics and Culturomicsapproaches of Bacterial and Viral Flora of Diabetic Foot Infection

Start date: December 2014
Phase: N/A
Study type: Observational

This work also highlights the presence of an unknown virus double-stranded DNA. In this project we propose 1) incorporating a bank of 150 samples from patients with diabetic foot infection in grades 2-4; 2) to study the microbial flora of a selection of 50 diabetic feet previously untreated with antibiotics for bacterial metagenomics, viral metagenomics and a minimum of 10 per culturomique; 3) to evaluate the use of targeted quantitative PCR on the most frequent new species frequency in the disease and incidentally get a sense of their role in the evolution and prognosis of the disease, including failures of and targeted antibiotic therapy on all 150 samples.