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Diabetic Foot clinical trials

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NCT ID: NCT05564728 Completed - Clinical trials for Diabetes Mellitus, Type 2

Diabetes Footcare Companion App for Patients and Carers

Start date: June 23, 2023
Phase:
Study type: Observational

Diabetes education and self-management support can be delivered via mobile phones. This protocol aims to assess the feasibility and acceptability of Well Feet, a conversational agent, as a diabetic foot care companion. By utilizing feedback and responses to evaluative questions posted on the app's interface, the investigators intend to examine the app's technical, functional, and operational feasibility.

NCT ID: NCT05556954 Recruiting - Diabetes Mellitus Clinical Trials

Diabetic Foot Ulcers Microbiome and Pathogen Identification

Start date: October 13, 2022
Phase:
Study type: Observational

This research is being done because people with diabetes have reduced healing capacity and prone to develop infections of foot wounds. This can be problematic because wounds that become infected may result in amputation and more severe complications. New evidence suggests that a better understanding of the microbiome of wounds (e.g., bacterial presence) may provide information about wound healing and provide an earlier opportunity to identify an individual who may be prone to develop diabetic foot infection in their wound. Therefore, the purpose of this study is to evaluate the role of the microbiome of the diabetic foot ulcer in development of infection and wound healing. Once the role of the microbiome is confirmed, progress towards the prevention and treatment of diabetic foot ulcers and complications may be possible.

NCT ID: NCT05553509 Recruiting - Clinical trials for Chronic Limb Threatening Ischemia

Clinical Outcomes Following Surgical Debridement of Diabetic Foot Infection With Borderline Vascularity

Start date: January 1, 2023
Phase:
Study type: Observational

Observe Timing to complete healing of wounds & Limb salvage in both cohorts those who are undergoing Debridement only and those who are undergoing Debridement plus PTA

NCT ID: NCT05551988 Completed - Diabetic Foot Ulcer Clinical Trials

Predictors of Foot Amputation in Diabetic Foot Ulcers

Start date: June 1, 2021
Phase:
Study type: Observational

Diabetes affects 463 million population of the world. Diabetic foot is one of the complications of uncontrolled diabetes which can lead to amputation in 5- 24% of non-healing diabetic foot ulcers. Every 30 seconds a lower extremity is amputated in the world due to diabetes. This is a retrospective study conducted in Balochistan, Pakistan. In this study investigators explored the risk factor of amputation in diabetic patients. Baseline characteristics, clinical profile, and lab tests were retrieved retrospectively and presented in the forms of tables. Investigators compared the categorical variables in amputees vs non-amputees and analyzed associated risk factors of amputation.

NCT ID: NCT05539963 Recruiting - Clinical trials for Diabetic Foot Osteomyelitis

A Feasibility Trial to Investigate the Safety and Between-group Effect Size of STIMULAN VG and Standard of Care (SoC) in Participants With Diabetic Foot Osteomyelitis of the Forefoot.

BLADE-VG2
Start date: January 23, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to evaluate the safety and between-group effect size of STIMULAN VG compared to SoC treatment in patients with diabetic foot osteomyelitis (DFO) of the forefoot.

NCT ID: NCT05530486 Recruiting - Diabetic Foot Clinical Trials

Effect of the Use of Low Intensity Therapeutic LASER

Start date: June 30, 2023
Phase: N/A
Study type: Interventional

Diabetes mellitus consists of a heterogeneous group of metabolic disorders that have hyperglycemia in common, resulting from defects in insulin action, insulin secretion, or both. Diabetes mellitus has gained increasing importance and is considered one of the main themes of global health problems due to the damage caused to quality of life, public health and the epidemiological picture presented. Among the complications are diabetic foot ulcers, with higher prevalence in the lower limbs, they are classified as loss of skin continuity, which can reach from the epidermis to deep structures such as muscles, bones and tendons.

NCT ID: NCT05519501 Recruiting - Diabetic Foot Ulcer Clinical Trials

Multi-Center, Randomized Controlled Clinical Investigation Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System in the Healing of Diabetic Foot Ulcers

Start date: October 10, 2021
Phase: N/A
Study type: Interventional

This is a randomized controlled multi center study on diabetic patients with the aim of evaluating the efficacy of the adipose tissue processed with the SyntrFuge™ system in diabetic patients with diabetic foot ulcers. In particular, it will be evaluated whether the microsized fat graft will be able to shorten the healing times of these wounds. Patients will be randomized to the treatment group with adipose tissue processed with the SyntrFuge™ system (injection of autologous microsized adipose tissue) or to the control group represented by the standard of care.

NCT ID: NCT05519163 Completed - Diabetic Foot Clinical Trials

A Study on Predictive Model for New-onset Diabetic Foot in Type 2 Diabetes Patients.

Start date: January 1, 2016
Phase:
Study type: Observational

A retrospective cohort study was constructed based on hospitalized patients with type 2 diabetes, aiming to explore the related factors for new-onset diabetic foot and conducted a robust prediction model by Cox proportional hazards model.

NCT ID: NCT05517863 Completed - Diabetic Foot Clinical Trials

The Effect of Combined 650 nm and Infrared Laser on Chronic Diabetic Foot Ulcer Surface Area:

wounds
Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Objective: investigate the effect of combined 650 nm and infrared laser on chronic diabetic foot ulcer surface area. Participants: The forty five patients will assigned randomly into three equal groups, each group consist of 15 patients, group A received laser therapy in sequential mode, group B received laser therapy in separate mode and the control group C receive traditional wound care

NCT ID: NCT05506215 Terminated - Diabetic Foot Clinical Trials

Randomized Clinical Study Comparing SynPath to Standard of Care in Treatment of Chronic Diabetic Foot Ulcers

DFUs
Start date: July 10, 2022
Phase: N/A
Study type: Interventional

The study will evaluate the efficacy of SynPath™, a synthetic dermal matrix, in the treatment of diabetic foot ulcers in subjects with diabetes mellitus versus Standard of Care treatment. Half the subjects with be treated using SynPath™ while the other half will receive Standard of Care treatment