Diabetic Foot Ulcers Clinical Trial
Official title:
A Prospective Study of Endothelial Dysfunction and Diabetic Foot Ulcer Risk
Verified date | January 2001 |
Source | VA Office of Research and Development |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Observational |
This project will identify risk factors for diabetic foot ulcer by studying the relationship
between endothelial dysfunction and foot ulcer risk. A fundamental defect in type 1 and 2
diabetic subjects is impaired vasodilatory reserve which is reflected in the dysfunction of
endothelium-dependent vasodilation. Findings thus far point to an important role of the
microvasculature in the development of diabetic foot ulcer and amputation.
In this study a a well-characterized cohort of 750 diabetic veterans without foot ulcer will
be followed over 3-years.
Status | Completed |
Enrollment | 750 |
Est. completion date | September 2002 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility | Diabetic patients with foot ulcers |
Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | VAMC, Seattle, WA | Seattle | Washington |
Lead Sponsor | Collaborator |
---|---|
VA Office of Research and Development |
United States,
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