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Umbilical Cord Blood Mononuclear Cell Gel in the Treatment of Refractory Diabetic Foot Ulcer — DFU-MNC  

Diabetic Foot Ulcer Clinical Trial

Official title:
The Efficacy and Safety of Umbilical Cord Blood Mononuclear Cell Gel in the Treatment of Refractory Diabetic Foot Ulcer.

Clinical Trial Summary

Umbilical cord blood mononuclear cells (MNC) may improve the wound repair ability. This study aims to investigate the role of MNC in refractory diabetic foot ulcer by comparing the combination of PRP and MNC with PRP alone.

Clinical Trial Description

The difficulty in the healing of diabetic foot is related to the loss of local repair microenvironment. The platelet rich plasma (PRP) can improve the repair ability, however, the requirement for wound bed preparation is strict, or treatment failure may occur. Umbilical cord blood mononuclear cells (MNC) may provide a better repair environment through paracrine action. This study aims to investigate the role of MNC in refractory diabetic foot ulcer by comparing the combination of PRP and MNC with PRP alone. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04689425
Study type Interventional
Source Peking University Third Hospital
Contact Long Zhang, Dr.
Phone +8613041210677
Email longzh2000@163.com
Status Recruiting
Phase Phase 3
Start date March 30, 2021
Completion date December 31, 2024
View Details
See also
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