Diabetic Foot Infection Clinical Trial
Official title:
Comparaison Entre la Performance du 18F-FDG PET/CT et de la Scintigraphie Osseuse/Gallium ou de la Scintigraphie Osseuse/Globules Blancs marqués /Souffre colloïdal Dans le Diagnostic d'Une ostéomyélite du Pied ou de la Cheville
Diabetic foot osteomyelitis is a common and serious complication of diabetes. While the
diagnosis of soft tissue infection can be made with simple physical examination in most
cases, bone involvement can be harder to diagnose, often requiring medical imaging. In
addition to conventional radiological examinations (x-ray and MRI) nuclear medicine
procedures can also provide important physiological information in these patients. These
procedures include triple phase bone scan combined with Gallium scintigraphy or a combination
of labelled leukocyte scintigraphy and bone marrow scintigraphy using sulfur colloid. These
procedure, while they provide useful physiological information, are time consuming, generally
requiring at least 2 separate image acquisition on separate days, and can be costly.
18F-FDG is a glucose analog that can be used for PET imaging. In addition to its application
in oncology, the literature has shown that FDG can be used to investigate a wide variety of
inflammatory and infectious conditions, including diabetic foot infections.
The aim of this study is to compare the usefulness of FDG PET imaging versus "conventional"
nuclear medicine (either bone scan and Gallium scintigraphy or labelled leukocytes and sulfur
colloid scintigraphy) in patient with suspected diabetic foot osteomyelitis.
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