Mechanisms Responsible for Cardiac and Skeletal Muscle Energetic Impairment in Diabetes — DDCM  

Diabetic Cardiomyopathy Clinical Trial

Official title: Mechanisms Responsible for Cardiac and Skeletal Muscle Energetic Impairment in Diabetes

Status Recruiting

Clinical Trial Summary

Diabetes increases the risk of heart failure. This is mainly due to a disease of the blood vessels supplying the heart muscle and/or high blood pressure, but abnormal metabolism may also contribute. We plan to study the mechanisms involved in this abnormal metabolism, whilst also assessing the effects of a drug called Perhexiline which improves the abnormal metabolism that is present in diabetic patients before the development of heart failure.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Cardiomyopathies
• Diabetic Cardiomyopathies
• Diabetic Cardiomyopathy

• NCT number: NCT00628056
• Study type: Interventional
• Source: University Hospital Birmingham
• Contact: Ganesh Nallur Shivu, MBBS MRCP
• Phone: 0044 1214145916
• Email: drgani23@gmail.com
• Status: Recruiting
• Phase: Phase 1/Phase 2
• Start date: October 2006
• Completion date: April 2009