Dexamethasone Clinical Trial
Official title:
Pilot Study of Methylprednisolone Replacement for Dexamethasone-induced Hiuup Patients
Dexamethasone is a potent synthetic member of the corticosteroid. It is given to cancer
patients undergoing chemotherapy to counteract emetic side effect and essential drug for the
chemotherapy-treated patients. Hiccup is common adverse effect of corticosteroid especially
on dexamethasone varying from 3% to 60% of given patients. Discontinuance of dexamethasone
relieves most hiccupping cases, but vomiting/nausea rates increase. It is not clear whether
hiccup side effect is limited to the dexamethasone only or other corticosteroid group.
Methylprednisolone, synthetic corticosteroid as similar as dexamethasone, could be
considered as antiemetic agent for the patients with receiving chemotherapy. The
investigators perform this pilot study under hypothesis that replacing dexamethasone with
methylprednisolone could maintain antiemetic role and prevent hiccup.
n/a
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT05549895 -
Effect of Intrathecal Dexamethasone on Intra-operative Hemodynamic in Elderly Patients Undergoing Urologic Endoscopic Surgery
|
Phase 4 | |
Recruiting |
NCT04025840 -
Perioperative Epidural Block and Dexamethasone in Pancreatic Cancer Surgery
|
Phase 4 | |
Completed |
NCT03688269 -
Minimal Effective Concentration (EC90) of Ropivacaine
|
Phase 3 | |
Recruiting |
NCT03043495 -
Dexamethasone Dose in Low Volume Bupivacaine USG Supraclavicular Block
|
Phase 4 | |
Completed |
NCT05070468 -
Effect of Dexamethasone on Labor Induction
|
Phase 3 | |
Completed |
NCT03874936 -
The Effect of Perioperative Dexamethasone Administration on Postoperative Pain in Patients Undergoing Periacetabular Osteotomy.
|
Phase 2/Phase 3 | |
Recruiting |
NCT06133712 -
Dexmedetomidine, Ozone and Dexamethasone Local Injection in Carpal Tunnel Syndrome for Pain Relief
|
N/A | |
Not yet recruiting |
NCT06044480 -
Effect of Dexamethason on Postimplantation Syndrome After EVAR
|
Phase 4 | |
Recruiting |
NCT04266977 -
Restrictive Use of Dexamethasone in Glioblastoma
|
N/A | |
Recruiting |
NCT02112864 -
Dexamethasone for Reduction of Post Thoracotomy Pain Syndrome
|
N/A | |
Not yet recruiting |
NCT05825378 -
The Effect of Intercostal Nerve Block With Dexamethasone and Ropivacaine on Rebound Pain After Thoracoscopic Surgery
|
N/A | |
Recruiting |
NCT05731960 -
Evaluating the Effect of Intravenous Dexamethasone on the Duration of Spinal Anesthesia After Cesarean Delivery
|
Phase 4 | |
Recruiting |
NCT04654507 -
Efficacy of Corticosteroids in Reducing Renal Scarring in Acute Pyelonephritis in Children
|
Phase 3 | |
Completed |
NCT03125941 -
High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy
|
Phase 4 | |
Unknown status |
NCT02178449 -
Prolongation of Pain Free Time by the Use of Dexamethasone in Peripheral Nerve Blockade
|
Phase 4 | |
Not yet recruiting |
NCT04763434 -
Dexamethasone and Dexmedetomidine as Adjuvants to Ropivacaine in Ultrasound-guided Multilevel Thoracic Paravertebral Block for Lobectomy: A Prospective, Randomized, Triple-blind Study
|
Phase 4 | |
Completed |
NCT04767256 -
Intravenous Dexamethasone and Dexmedetomidine on the Analgesic Efficacy of Erector Spinae Plane Block
|
N/A | |
Completed |
NCT03456752 -
Perioperative Dexamethasone on Postoperative Outcome in IBD
|
Phase 2 | |
Completed |
NCT06085417 -
Comparison of the Effects of Dexamethasone and magnesıum Sulphate Used as Adjuvant in Infraclavicular Nerve Block.
|
N/A | |
Completed |
NCT04714112 -
Low-dose Intravenous Dexamethasone at Different Times as Adjunvants for Brachial Plexus Blocks
|
Phase 4 |