Morphofunctional Imaging and Developmental Dyslexia

Developmental Dyslexia Clinical Trial

— PHR04-CH/DYS  

Official title:

Morphofunctional Imaging and Developmental Dyslexia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00254644
• Other study ID #: PHRR04-CH/DYS
• Status: Completed
• Phase: N/A
• First received: November 15, 2005
• Last updated: January 13, 2017
• Start date: February 2007
• Est. completion date: February 2008

Study information

• Verified date: May 2011
• Source: University Hospital, Tours
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Developmental dyslexia is a frequent learning disability. The aim of this study is to analyze cortical thickness and phonological treatment in right handed adults with developmental dyslexia. They are compared to control adults paired with age and laterality. To study phonological treatment, the researchers used functional magnetic resonance imaging (fMRI) with a rime judgement task and silent word generation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 32
• Est. completion date: February 2008
• Est. primary completion date: February 2008
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Developmental dyslexia according to Critchley.

• Normal performance intelligence quotient (PIQ)

• Age: 18-35 years

• Sex: Male

• Right handed

• No hearing deficit.

Exclusion Criteria:

• No head injury

• No attention deficit hyperactivity disorder (ADHD)

Related Conditions & MeSH terms

• Developmental Dyslexia
• Dyslexia

Intervention

Procedure:
• Morphological and functional MRI
one time

Locations

Country	Name	City	State
France	CHU	Tours

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Tours

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cortical thickness	The average cortical thickness maps of healthy subjects and dyslexic will be compared hemisphere by hemisphere. This will identify whether there are cortical areas including cortical thickness differed significantly between normal and dyslexic.ts of different ages	2 years
Secondary	Average cortical thickness	For each group, cortical thickness maps of average left and right hemispheres are compared. This will identify whether there is an asymmetry left / right in terms of cortical thickness in normal subjects and dyslexic.	2 years