Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults

Development Clinical Trial

— TNNS  

Official title:

Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02646956
• Other study ID #: NIH DC011287
• Status: Completed
• Phase: N/A
• First received: December 18, 2015
• Last updated: January 4, 2016
• Start date: May 2014
• Est. completion date: September 2015

Study information

• Verified date: December 2015
• Source: Monell Chemical Senses Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The goal of the study is to determine whether there are age-, diet- and genetically-related differences in the perception of sweeteners, both nutritive and non-nutritive.

Description:

This is an observational 3-day study of children between the ages of 7 and 14 and their mothers. A variety of psychophysical methods determined liking for each of the sweeteners and saliva samples were obtained for genotyping of taste receptor genes. Anthropometric and dietary intake measures were also collected.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 82
• Est. completion date: September 2015
• Est. primary completion date: September 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 7 Years to 60 Years

Eligibility

Inclusion Criteria:

• Healthy

Exclusion Criteria:

• Allergies and taking medication that affected taste

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Development

Intervention

Other:
• sweeteners
Participants tasted a variety of nutritive and nonnutritive sweeteners

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Monell Chemical Senses Center

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Liking for the taste of sweeteners measured via the 3-point facial hedonic scale.		Through study completion, an average of 6 months.	No
Primary	Liking for the taste of sweeteners measured via the 5-point facial hedonic scale		Through study completion, an average of 6 months.	No
Primary	Liking for the taste of sweeteners measured via the Monell forced-choice, paired-comparison tracking procedure.		Through study completion, an average of 6 months.	No
Secondary	Genotyping of taste receptor genes via saliva donation	Genotyping will be completed to measure associations between individual taste receptor genotypes and liking of sweeteners.	Through study completion, an average of 6 months	No
Secondary	BMI calculated from body weight and height measures	BMI will be calculated to examine associations between this measure and liking for sweeteners.	Through study completion, an average of 6 months	No
Secondary	One day dietary intake collected via the Automated Self-Administered 24-hour dietary recall (ASA24).	Dietary recall will be completed to examine associations between added sugar intake and liking for sweeteners.	Through study completion, an average of 6 months	No