Clinical Trials Logo

Clinical Trial Summary

Desmoid tumors, also called aggressive fibromatosis, are rare, locally invasive tumors with no potential for metastasis. The incidence is approximately 2 to 4 per million per year in the general population. The "watch and wait" policy is the standard of care for newly diagnosed patients in Europe. Patients who progress have first-line medical treatment, surgery is no longer the treatment because there is a high rate of recurrence (> 60%) and radiotherapy is not very suitable because the patients are often young and the tumors are large. Cryoablation seems to be an effective therapeutic option that should be evaluated.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06113094
Study type Observational
Source University Hospital, Strasbourg, France
Contact Pierre AULOGE, MD
Phone 33 3 69 55 15 26
Email pierre.auloge@chru-strasbourg.fr
Status Recruiting
Phase
Start date July 7, 2020
Completion date December 31, 2023

See also
  Status Clinical Trial Phase
Completed NCT01981551 - Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis Phase 2
Withdrawn NCT00978146 - Effect of Hydroxyurea as Treatment for Primary Desmoid Tumors Phase 2
Completed NCT02476305 - Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment N/A