Gastroesophageal Reflux Disease Clinical Trial
Official title:
Association Between Cardiorespiratory and Gastroesophageal Reflux Events in Infants.
Cardiorespiratory and gastroesophageal reflux events often coexist in infants in Neonatal
Intensive Care Unit (NICU) thus leading to drugs over-prescription and delayed discharge.
Through cardiorespiratory and pH-impedance monitoring this study aims to evaluate the
temporal association between gastroesophageal reflux (GER) and cardiorespiratory (CR) events
in a large number of infants with gastroesophageal reflux disease (GERD) and CR symptoms
and, whether this association is significant, to clarify the impact of GER on CR events.
This is an observational retrospective study to describe the association between
cardiorespiratory (CR) and gastroesophageal reflux (GER) events in infants who underwent
synchronized 24h Multichannel Intraluminal Impedance/pH-metry (MII/pH) and CR monitoring for
GER disease symptoms and CR events. Data are collected from medical records and database of
the University Neonatal Intensive Care Unit of the Sant'Anna-Regina Margherita Children
Hospital (Turin).
The symptom association probability (SAP) index is used to identify those infants with
significant associations between GER and CR events. In the group of infants with a positive
SAP index the differences in reflux characteristics are compared according to whether a
reflux preceded or followed a cardiorespiratory event (30 s time window).
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02135107 -
A Double-blind Comparative Study of the Efficacy and Safety of E3810 10mg Once and Twice Daily in Maintenance Therapy for PPI Resistant Gastroesophageal Reflux Disease Patients
|
Phase 3 | |
| Completed |
NCT01432392 -
Symptom Control and Impact on Daily Life in Patients With Gastroesophageal Reflux Disease
|
N/A | |
| Recruiting |
NCT01249482 -
Symptom Assessment for GERD Patients Receiving H. Pylori Eradication
|
N/A | |
| Completed |
NCT01200550 -
The Study to Describe Symptom Control and Impact on Daily Life in Gastroesophageal Reflux Disease (GERD) Patients
|
N/A | |
| Completed |
NCT01578642 -
Feasibility Study for Evaluating the Effect of Electrical Stimulation on Lower Esophageal Sphincter Pressure and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease
|
Phase 2 | |
| Completed |
NCT00998244 -
Study to Evaluate the Effect of a Very Low Carbohydrate Diet on Gastroesophageal Reflux Disease
|
N/A | |
| Completed |
NCT00978016 -
A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)
|
Phase 2 | |
| Unknown status |
NCT01128608 -
The Effect of High PCO2 Solution on Esophageal Acid Sensation
|
N/A | |
| Completed |
NCT00768196 -
Prevalence of EED and Quality of Life Evaluated by Gastroesophageal Reflux Disease (GERD)-Q in Korean GERD Patients
|
N/A | |
| Completed |
NCT00768443 -
Symptoms and Management Strategies in Gastroesophageal Reflux Disease (GERD)
|
N/A | |
| Recruiting |
NCT00498082 -
Determinants of Efficacy of EsophyX Treatment in Gastro-Esophageal Reflux Disease
|
N/A | |
| Completed |
NCT00886197 -
Diagnostic Efficacy of Narrow Band Imaging in Patients With Gastroesophageal Reflux Disease
|
N/A | |
| Completed |
NCT00378898 -
Feasibility of Placing Bravo PH Capsule in Proximal Esophagus
|
N/A | |
| Completed |
NCT00507377 -
Foreshortened Esophagus and Its Surgical Therapy
|
||
| Completed |
NCT00217347 -
Evaluation of Efficiency of Esophageal Capsule Endoscopy in the Screening of Patients With Gastroesophageal Reflux Disease or Dyspepsia as Compared to Upper Endoscopy
|
N/A | |
| Completed |
NCT00165022 -
Development of a Novel Disease-Specific Quality of Life Questionnaire for Gastroesophageal Reflux Disease (GERD) Patients in Chinese Population
|
N/A | |
| Completed |
NCT00214552 -
Evaluate the Effects on Asthma Control of Rabeprazole Given Twice Daily in Subjects With Asthma.
|
Phase 3 | |
| Completed |
NCT00625495 -
Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)
|
Phase 4 | |
| Completed |
NCT00618150 -
Patient Education in Gastroesophageal Reflux Disease
|
N/A | |
| Completed |
NCT03299985 -
Diaphragmatic Myofascial Release in Gastroesophageal Reflux Disease
|
N/A |