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Dermatologic Disorders clinical trials

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NCT ID: NCT02383680 Recruiting - Clinical trials for Dermatologic Disorders

Yellow Fever Vaccination Under Low Dose Methotrexate Therapy

MTX_YF
Start date: December 2014
Phase: N/A
Study type: Observational

Travelers (n = 30, 15 taking low-dose methotrexate (MTX), 15 healthy controls (HC), seeking travel advice in one of the following Swiss Travel Centers (Aarau, Basel, Bern, Geneva, Lausanne, Zurich) and who have an indication for yellow fever (YF) vaccination according to the Swiss Federal Office of Public Health's vaccination recommendations are invited to participate in this study. After signing the consent form (i) YF viremia and (ii) anti-YF antibody production in patients taking low-dose MTX and HC will be compared after YF vaccination. It will be analyzed whether the percentage of people with protective antibodies differs between the two groups and (iii) vaccine side effects will be compared between the groups.