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Dermatitis clinical trials

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NCT ID: NCT03779295 Withdrawn - Perioral Dermatitis Clinical Trials

Laser Therapy for Perioral Dermatitis

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Perioral dermatitis is an inflammation of the skin around the mouth. The cause of perioral dermatitis is unknown. Current treatment methods include oral antibiotics and topical calcenurin inhibitors, both of which produce side effects and have been relatively ineffective in the treatment of perioral dermatitis. The investigators hope to assess the efficacy of laser therapy in treatment of perioral dermatitis by using laser therapy on one half of the patients face and having patients apply topical medication (clindamycin) to their face for 8 weeks. The side of their face that receives laser therapy will be randomized. The investigators will assess the efficacy of laser therapy by counting the number of lesions that patients have before and after laser therapy, comparing photos of patient's perioral dermatitis before and after treatment, and having patient's rate their satisfaction of the treatment.

NCT ID: NCT03741933 Withdrawn - Clinical trials for Chronic Hand Dermatitis

Apremilast and Moderate to Severe Chronic Hand Dermatitis

CHD
Start date: February 28, 2019
Phase: Phase 4
Study type: Interventional

Investigators have designed a pilot study involving chronic hand dermatitis (CHD) patients who attend the dermatology clinic at the George Washington Medical Faculty Associates (GW MFA) in order to assess the efficacy and safety of apremilast treatment for the treatment of moderate to severe CHD.

NCT ID: NCT03710044 Withdrawn - Atopic Dermatitis Clinical Trials

Investigation of Flare and Remission in Subjects With Atopic Dermatitis

Start date: August 2019
Phase: Phase 4
Study type: Interventional

The trial is an exploratory, single-centre, uncontrolled, open-label, interventional trial of up to 19 weeks' duration to investigate flare and remission in subjects with moderate-to-severe atopic dermatitis (AD) treated with cyclosporine A (CsA).

NCT ID: NCT03688464 Withdrawn - Atopic Dermatitis Clinical Trials

Treatment of Nighttime Pruritus in Atopic Dermatitis

Start date: April 1, 2018
Phase: Early Phase 1
Study type: Interventional

This study will look at melatonin vs. first generation antihistamine vs. placebo in improving nighttime itching in children with atopic dermatitis.

NCT ID: NCT03553615 Withdrawn - Atopic Dermatitis Clinical Trials

Open-label Pilot Clinical Trial of Oral Ivermectin to Treat Atopic Dermatitis

Start date: December 2018
Phase: Phase 2
Study type: Interventional

This pilot trial studies how well a novel oral therapeutic agent performs to treat patients with atopic dermatitis, particularly facial dermatitis.

NCT ID: NCT03464526 Withdrawn - Atopic Dermatitis Clinical Trials

A Study of the Efficacy and Safety of Orvepitant in Subjects With Pruritus Associated With Atopic Dermatitis

SOOTHE
Start date: May 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness of three doses of orvepitant, taken once a day, in the treatment of pruritus associated with atopic dermatitis.

NCT ID: NCT03089476 Withdrawn - Atopic Dermatitis Clinical Trials

Evaluating Skin Barrier Dysfunction in Infants at High Risk of Atopy

Start date: September 30, 2017
Phase: N/A
Study type: Interventional

It is hypothesized that food allergy is preceded by atopic dermatitis (AD), due to a disruption of skin barrier which can predispose one to food sensitization through the skin. The central hypothesis is that increased transepidermal water loss (TEWL) assessment and skin tape strip analysis (STS) of lipid and filaggrin breakdown products will be predictive markers for the development of AD. Additionally, the associated changes in TEWL and STS will further improve the identification of infants at risk of early food sensitization, compared to family history alone.

NCT ID: NCT03000595 Withdrawn - Atopic Dermatitis Clinical Trials

A Trial of a Botanical Drug Product Containing East Indian Sandalwood Oil (EISO) For Treatment of Atopic Dermatitis

Start date: June 2018
Phase: Phase 2
Study type: Interventional

This trial will be a double-blind, randomized, placebo-controlled, safety, tolerability and efficacy trial of SAN007 (5% East Indian sandalwood oil in a cream formulation) treatment regimen when administered daily for up to 28 days to patients from 3 months to 65 years of age, with atopic dermatitis.

NCT ID: NCT02842372 Withdrawn - Clinical trials for Acute Graft Versus Host Disease in Skin

Ectoin Dermatitis Cream 7% as First-line Therapy of Acute Skin Graft Versus Host Disease

Start date: December 2015
Phase:
Study type: Observational

This is a non-interventional prospective study to investigate the treatment response to topical application with Ectoin Dermatitis Cream 7% as first-line therapy of grade I acute skin graft-versus-host disease.

NCT ID: NCT02677636 Withdrawn - Atopic Dermatitis Clinical Trials

Efficacy and Safety Study of MSRD-100 in Subjects With Atopic Dermatitis >=3 Months of Age and Older

MSRD-100
Start date: n/a
Phase: Phase 3
Study type: Interventional

This is a double-blind, randomized, vehicle-controlled, multi-center, parallel group Phase 3 study of MSRD-100 in the treatment of atopic dermatitis in subjects aged 3 months and up