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Dermatitis, Contact clinical trials

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NCT ID: NCT05508243 Completed - Clinical trials for Sensitivity, Contact

Dermatological Assessment of Primary Dermal Irritability Accumulated and Sensitization of Hyaluronic Nasal Spray

Start date: October 17, 2022
Phase: N/A
Study type: Interventional

Evaluate the potential of Primary Dermal Irritability, Accumulated Dermal Irritability and Dermal Sensitization, of health products through the application of Patch Test, proving the safety of the product for topical use. The study will be conducted with a Brazilian sample in which 65 research participants will be included. Depending on the results, the present study may support the claim: dermatologically tested.

NCT ID: NCT05508230 Completed - Clinical trials for Sensitivity, Contact

Evaluation of Cutaneous Acceptability and Perceived Effectiveness of a Nasal Spray (Health Care Products)

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

This is a clinical study for health care product safety assessment. The research is going to conducted with 45 subjects, aged 18 to 70 years, women users of the product category, regardless of color/race, ethnicity, sexual orientation, classes and social groups and who must present all the other characteristics of the inclusion criteria and no exclusion characteristics. The product is applied under real conditions of use, in a panel of survey participants corresponding to the target consumers. Medical evaluation will be available throughout the study to assess possible adverse events. The main of the study is to observe the effects of the application of the product on the skin and prove the absence of irritability and/or allergy and perceived acceptability.

NCT ID: NCT05497921 Completed - Clinical trials for Contact Dermatitis of Hand

Crossover Study to Evaluate the Efficacy of LED in Treating the Signs of Contact/Irritant Dermatitis of the Hand

Start date: October 7, 2022
Phase: N/A
Study type: Interventional

This study is intended to be a cross over study. Subjects will treat one hand while the contralateral hand acts as a control. At the end of 6 weeks the subject will be instructed to cease treatment of the test hand and commence treatment of the control hand for 6 weeks. Efficacy will be evaluated at 6 weeks after the beginning of the treatment and 12 weeks (end of crossover).

NCT ID: NCT05339750 Completed - Clinical trials for Allergic Contact Dermatitis

Allergy Skin Patch Artificial Intelligence (AI)

Start date: February 15, 2022
Phase: N/A
Study type: Interventional

The purpose of this research is to assess human and artificial intelligence performance in grading contact dermatitis reactions in healthy volunteers.

NCT ID: NCT05320315 Completed - Clinical trials for Polymorphic Light Eruption

Protective Effect Assessment of Foto Ultra Isdin Solar Allergy Fusion Fluid on the UVA Induced PLE

Start date: February 25, 2021
Phase: N/A
Study type: Interventional

The primary objective of this Clinical Investigation was to assess the protective efficacy of a medical device (FOTO ULTRA ISDIN® SOLAR ALLERGY FUSION FLUID) against the polymorphic light eruption induced by the UVA. The secondary objective of this Clinical Investigation was to assess the local safety and the overall tolerability of the test MD on the basis of AE/SAE reporting.

NCT ID: NCT04921163 Completed - Contact Dermatitis Clinical Trials

Children With Aluminium Contact Allergy: Oral Exposure Study

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Aluminium allergy is predominantly seen in children with small itchy nodules in the skin after vaccinations, so-called granulomas. We want to do an exposure study where aluminium allergic children have to eat aluminium pancakes for a short period of time. The purpose is to investigate whether a worsening of the children's symptoms can be detected, both itching of the granuloma, allergic rash on the skin and also the symptoms that are not measurable, such as headache, stomach ache and general agitation. We also want to examine the concentration of aluminium in the urine, which reflects the absorption of aluminum from the gastrointestinal tract.

NCT ID: NCT04790799 Completed - Clinical trials for Occupational Contact Dermatitis

Occupational Hand Eczema - Testing of a Prevention-concept

Start date: July 2, 2020
Phase: N/A
Study type: Interventional

Randomised controlled trial examining the effect of decreased waiting time for the first doctors' appointment, patient education, glove counselling and counselling at departments of social or occupational medicine on severity of hand eczema, quality of life, use of corticosteroids, and jobsituation 3-12 months after intervention in patients with suspected occupational contact dermatitis of the hands.

NCT ID: NCT04772482 Completed - Dermatitis Clinical Trials

Study on Hypoallergenic Hair Dye

Start date: April 1, 2021
Phase:
Study type: Observational

Permanent hair dyes are commonly used in over the counter direct to consumer products and within hair salons. Allergy, also known as contact dermatitis, to hair dye is a well known phenomenon. Herein, we seek to decrease the risks of allergy to hair dyes by testing a novel version of p-phenylenediamine (PPD) with less allergy potential.

NCT ID: NCT04704713 Completed - Clinical trials for Polymorphic Light Eruption

Afamelanotide in Patients Suffering From Polymorphic Light Eruption (PLE)

Start date: May 5, 2010
Phase: Phase 3
Study type: Interventional

This study was to evaluate the safety and efficacy of afamelanotide in patients suffering from polymorphic light eruption (PLE).

NCT ID: NCT04438135 Completed - Contact Dermatitis Clinical Trials

Children With Aluminium Contact Allergy: Cutaneous Exposure Study

Start date: June 10, 2020
Phase: N/A
Study type: Interventional

Aluminium is used in many different cosmetic products, including make-up, deodorants and sunscreen. The purpose of this study is to investigate whether these everyday skin products with small amounts of aluminium can cause skin reactions in children diagnosed with contact allergy to aluminium. The study is conducted as a Repeated Open Application Test study (ROAT), a method originally developed to clarify the clinical relevance of questionable and positive patch samples, by imitating everyday use of a skin product.