Dermatitis, Allergic Contact Clinical Trial
Official title:
Cutaneous and Systemic Reactions to Metal Implants: Utility of Patch Testing Prior and Post Placement of Metal Orthopedic Implants
The purpose of this study is to evaluate if metal patch testing in metal allergic patients is useful for predicting the development of allergic skin disease or systemic symptoms in patients who recieve a metal orthopedic implant.
This prospective cohort study will enroll patients with a history of metal allergy who
require implantation of a metal orthopedic device. Patients will be followed for one year
after surgery to determine if any symptoms including rash, itch, joint pain, joint swelling,
and/or joint failure develop post implantation.
Patients will be recruited from two sites: (1) Divisions of Orthopedics and Allergy &
Immunology, Winthrop University Hospital, and (2) Division of Immunology, and Allergy
Section, University of Cincinnati Medical Center.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00141180 -
CP-481,715 Nickel Allergy Study.
|
Phase 1 | |
| Completed |
NCT01953380 -
Intervention Study to Evaluate the Importance of Information Given to Patients With Contact Allergy
|
N/A | |
| Completed |
NCT00928447 -
Study of the Intradermal Injection of rHuPH20 or Placebo in Participants With Nickel Allergic Contact Dermatitis
|
Phase 2 | |
| Completed |
NCT04182425 -
Incidence of Allergic Manifestations and Infectious Episodes in Healthy Term Infants at Risk for Dysbiosis
|
||
| Completed |
NCT03522675 -
NeoMatriX Wound Matrix Collagen Dressing Skin Prick Test
|
N/A |