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Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity

Dentin Sensitivity Clinical Trial

Official title:
Randomized Non-inferiority Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity

Clinical Trial Summary

Subjects will be enrolled into 3 balanced groups each using a different strength toothpaste. Dental hypersensitivity (DHS) will be assessed at study start, midway and study end.

Clinical Trial Description

This study is a double-blind, randomized, placebo-and positive-controlled, stratified parallel group clinical trial. The three groups will be randomly assigned to use one of three test toothpastes having an identical base formulation but containing respectively either 0% nano-hydroxyapatite (HAP) (placebo), 15% nano-HAP or 5% KNO3 (positive control). All dental examinations for data collection will be conducted by the same Clinical Examiner. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04590040
Study type Interventional
Source The University of Texas Health Science Center at San Antonio
Contact
Status Completed
Phase N/A
Start date July 28, 2020
Completion date March 1, 2023
View Details
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