Dentin Sensitivity Clinical Trial
Official title:
A Study to Evaluate the Efficacy of an Experimental Occlusion Technology Dentifrice in the Relief of Dentinal Hypersensitivity
This study will evaluate the effectiveness of an experimental dentifrice containing stannous fluoride, an established dentine tubule occlusion technology, at reducing dentine hypersensitivity (DH) compared to a negative control dentifrice. The test and control dentifrices will be administered for a total of 8 weeks, with assessments (via evaporative air and tactile stimuli) at baseline, and after 4 and 8 weeks twice-daily use.
This single centre, randomized, controlled, examiner-blind, 2 treatment arm, parallel group design study, stratified by maximum baseline Schiff sensitivity score (of the two selected teeth), with a treatment period of 8 weeks will investigate the clinical effectiveness of an experimental stannous fluoride dentifrice in the reduction of DH. DH will be assessed at Baseline, and after 4 and 8 weeks treatment to monitor clinical efficacy and safety. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02753075 -
A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.
|
N/A | |
| Completed |
NCT06045026 -
A Real-World Evidence Study Evaluating Oral Health Related Quality Of Life With Use Of A Stannous Fluoride Anti-Sensitivity Toothpaste For Dentin Hypersensitivity Management
|
N/A | |
| Completed |
NCT02542943 -
Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity
|
N/A | |
| Completed |
NCT02226562 -
Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity
|
Phase 2 | |
| Completed |
NCT02919202 -
Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
|
N/A | |
| Not yet recruiting |
NCT04485299 -
Clinical Assessment of Bifluorid 10 vs Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient
|
Phase 2/Phase 3 | |
| Completed |
NCT02931734 -
Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment
|
N/A | |
| Completed |
NCT02923895 -
To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH)
|
Phase 4 | |
| Withdrawn |
NCT03361774 -
A Clinical Method Development Study to Characterise The Efficacy of a Dentifrice For The Relief Of Dentin Hypersensitivity
|
Phase 2 | |
| Completed |
NCT02924350 -
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (DH)
|
N/A | |
| Completed |
NCT05083052 -
Propolis in Reducing Dentin Hypersensitivity
|
N/A | |
| Active, not recruiting |
NCT06150573 -
A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching
|
N/A | |
| Completed |
NCT02937623 -
To Evaluate the Efficacy of an Experimental Dissolvable Strip in Rapidly Relieving Dentinal Hypersensitivity (DH)
|
N/A | |
| Completed |
NCT02612064 -
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
|
N/A | |
| Completed |
NCT02293044 -
A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity
|
N/A | |
| Completed |
NCT02128633 -
Effectiveness of a Homecare Dentin Hypersensitivity Gel
|
Phase 2/Phase 3 | |
| Completed |
NCT03310268 -
A Clinical Study to Evaluate a Stannous Fluoride Toothpaste for the Relief of Dentinal Hypersensitivity
|
N/A | |
| Completed |
NCT05750745 -
A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste for the Relief of Dentine Hypersensitivity in a Chinese Population
|
N/A | |
| Not yet recruiting |
NCT06417580 -
Effect of Pregabalin Gel in Controlling Cervical Dentin Hypersensitivity
|
Phase 2 | |
| Completed |
NCT02752958 -
Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health
|
N/A |