Evaluation of Apexogenesis With Human Treated Dentin Matrix in Young Permanent Molars

Dentin Bridge Clinical Trial

Official title: Clinical, Radiographic and Tomographic Evaluation of Apexogenesis With Human Treated Dentin Matrix in Young Permanent Molars

Status Completed

Clinical Trial Summary

Assess the clinical, radiographic, and tomographic outcomes of apexogenesis with human treated dentin matrix in young permanent molars compared to MTA.

Clinical Trial Description

The study was conducted as a split-mouth randomized clinical trial, approved by research ethics committee, Faculty of Dentistry, Tanta University, and carried out at Pediatric Dentistry Department, Faculty of Dentistry, Tanta University. The material preparation was conducted at Pharmaceutical Technology Department, Faculty of Pharmacy, Tanta University. 20 children of both sexes aged from 6 to 8 years old were selected with bilateral deeply carious young permanent mandibular first molars that are indicated for vital pulp therapy.The selected deeply carious molars were randomly divided into two groups as follows:

Group I (Study group): 20 molars were treated with human TDM. Group II: (Control group): 20 molars were treated with White MTA. The participating cases were evaluated clinically and radiographically after 6, 12 and 18 months. Tomographic evaluation was performed immediate postoperatively and at 18 months. ;

Related Conditions & MeSH terms

• Dentin Bridge

• NCT number: NCT05830695
• Study type: Interventional
• Source: Tanta University
• Status: Completed
• Phase: Phase 1/Phase 2
• Start date: January 18, 2022
• Completion date: March 31, 2023