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Clinical Trial Summary

An individual's quality of life can be seriously affected by the severity of dental pain. The emergency department is a common place to find those seeking relief from their dental pain- often times seeking removal of the affected tooth, dental anesthetic injections or oral pain medications. There are a number of dental infections that cause this type of debilitating pain. One such dental infection is termed periapical abscess. This infection involves the tooth pulp. These infections can arise in three ways: introduction through a defect in the enamel and dentin; from a periodontal pocket or an adjacent tooth; or hematogenous seeding of the pulp from mechanical irritation. As this disease process continues there are a number of complications including chronic pain and, more seriously, the spread of infection into deep spaces which can be a life threatening condition.

The Emergency Department treatment of this infection includes pain control, antibiotics and dental referral for ultimate management of the infection.

The purpose of our study is to investigate whether the addition of oral steroids will alter the time until patient experiences improvement in their dental pain. Steroids are a commonly used anti-inflammatory that is used in the Emergency Departmentfor the purpose of pain relief from throat pain. As the pain from periapical infection is thought to be largely from the pressure we speculate that the anti-inflammatory effects of steroids may decrease the inflammation thus the pressure and may ultimately lead to a decrease in time until the patient experiences some relief from their pain.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT03005522
Study type Interventional
Source University of Arizona
Contact Susanne Olkkola, MEd, MPA
Phone 520-626-8819
Email [email protected]
Status Recruiting
Phase N/A
Start date January 2017
Completion date December 2019

See also
  Status Clinical Trial Phase
Recruiting NCT03967002 - Treatment of the Mandibular Dental Crowding With and Without Corticotomy Surgery N/A