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Dental Pulp Regeneration clinical trials

View clinical trials related to Dental Pulp Regeneration.

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NCT ID: NCT04190914 Completed - Primary Teeth Clinical Trials

Different Treatment Modality in Necrotic Primary Molars

Start date: February 7, 2020
Phase: N/A
Study type: Interventional

Necrotic primary molars in preschool children will be treated with the regeneration concept to provide a healthy biological environment within the root canal system and regression in clinical signs and symptoms which are the primary outcomes of regeneration treatment.

NCT ID: NCT03833401 Recruiting - Clinical trials for Dental Pulp Regeneration

Dental Pulp Regeneration by Autologous Tissue Transplantation

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to develop new improved therapy for teeth that require root canals due to tooth infection or tooth inflammation. Investigators will recruit total of 50 participants from the age group 7 - 50 at the UCLA School of Dentistry Endodontic clinic. The participants will be divided into two groups, one will receive traditional therapy, which may include root canal or a procedure called "revascularization," which is a procedure trying to regrow the tissue inside the tooth. The other group of participants will receive the test treatment, which will involve harvesting of pulp tissues from the same tooth or other teeth that are planned for extraction. Investigators will prepare these tissues and place the tissues back into the cleaned root canal space with induced bleeding to allow regrowth of the tissue. For all participants, investigators will follow up after 6, 12, and 24 months in a shorter appointment, which may involve taking x-ray and clinical exam.

NCT ID: NCT02842515 Completed - Clinical trials for Dental Pulp Regeneration

Feasibility of the Preparation of an Advanced Therapy Medicinal Product for Dental Pulp Regeneration

Pulp'R
Start date: January 2015
Phase: N/A
Study type: Observational

Current endodontic treatment are based essentially on the ouster of parenchyma in case of trauma or irreversible pulp inflammation. These situations typically affect immature teeth in subjects aged from 8 to 15 years. Consequently, loss of a functional pulp is leads to discontinuation of root development and apical closure. The challenge for the clinician in the management of such situations is then preserving a pulp vitality. But current practices consist in a filling of the endo-canal system with an inert or semi-inert material. In this case, no pulp vitality is present. New treatment methods are needed. The objective Pulp'R is the study the feasibility of preparing an autologous combined advanced therapy medicinal product (ATMP) for dental pulp regeneration in the patient with irreversible pulp inflammation or dental trauma.

NCT ID: NCT01805388 Withdrawn - Clinical trials for Dental Pulp Regeneration

Comparison of Tissue in Regenerative Endodontic Procedures and Apexification

Start date: February 2013
Phase: Phase 1
Study type: Interventional

The purpose of our study is to characterize the composition of the hard and soft tissues present after regenerative endodontic procedures in root canals of teeth previously diagnosed with the need for extraction for orthodontic treatment and incomplete root formation. Although the protocol addressed in this study is currently being used in clinical practice, there are no prospective clinical trials investigating its efficacy in stimulating continued root development and the nature of the newly formed tissues.

NCT ID: NCT00595595 Completed - Clinical trials for Dental Pulp Diseases

Development of a Model to Evaluate Regenerative Endodontic Techniques Using Extract Human Teeth

Start date: February 2007
Phase: N/A
Study type: Observational

Millions of teeth are saved each year by root canal therapy. Although current treatment modalities offer high levels of success for many conditions, an ideal form of therapy might consist of regenerative approaches in which diseased or necrotic pulp tissues are removed and replaced with healthy pulp tissue in order to revitalize teeth.