Dental Caries Extending to Pulp Clinical Trial
Official title:
Long-term Evaluation of Direct Pulp Capping Using Either Mineral Trioxid Aggregate or Calcium Hydroxide in Permanent Mature Teeth: A Randomized Controlled Trial
Calcium hydroxide and mineral trioxide aggregate have been used in vital pulp therapy with variable outcomes recorded by different study. They will be compared when used for direct pulp capping in cariously exposed mature permanent teeth.
Vital pulp therapy has the benefit of providing patients with a conservative treatment option
with relatively low cost when compared to conventional root canal treatment and spares them
possible post-treatment consequences that might occur. Vital pulp treatment in trauma cases
is associated with high success rate but controversy still exists regarding vital pulp
treatment in carious-exposed pulp.
The purpose of this study is to evaluate the success rate of direct pulp capping performed
with MTA-Angelus® or calcium hydroxide in mechanical-exposed or carious-exposed mature
permanent human teeth. Patients included in this study will be recruited from routine dental
patients attending conservative clinics in JUST Dental Teaching Centre. Adult patients
scheduled for routine conservative treatment involving caries removal and restoration with
mechanical or carious pulp exposure will be invited to participate in this study.
A total of 80 carious human teeth with carious pulp exposure will be included in this
randomized clinical study. Patients are among those scheduled for conservative dental
treatment and end with pulp exposure. The patients and/or their parents will be asked to sign
a consent form after receiving a detailed explanation about the study rationale, clinical
procedures, and possible risks. The exposed teeth will be divided randomly into two
experimental groups (n=40) according to the dressing materials; MTA-Angelus® or calcium
hydroxide, then teeth will be restored with permanent filling. Teeth will be reviewed
recording any signs and symptoms. Patients will be reviewed in 1 week, 3 months and yearly
after. MTA-Angelus and calcium hydroxide are anticipated to be biocompatible and induce hard
tissue barrier. This project will reveal if tested materials are presented with promising
profile upon using as direct pulp capping dressing in mechanical and carious-exposed pulp.
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