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Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

Dental Prosthesis Clinical Trial

Official title:
Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers

Clinical Trial Summary

The purpose of this study is to determine if MI Paste affects the bacteria and fungus present within the mouth, as well as to determine if MI Paste increases denture comfort and retention. MI Paste is a water-based topical dental product that is available without a prescription. It is generally used to treat dental/tooth hypersensitivity (sensitive teeth) in patients and/or to help re-mineralize the tooth enamel in patients. Within this study, there is an off-label use for research subjects to apply above the upper denture.

Clinical Trial Description

Potentially-eligible subjects will be invited to the research study that involves consenting and 4 in-person visits (Screening Visit, Visit 1, Visit 2, Visit 3) where the following will be performed at each visit: (i) upper denture/mouth tissues swab sample collected, (ii) survey questions being administered, and (iii) brief oral dental exam (clinical assessment). Furthermore, at Visit 2, subjects will be provided and instructed on how to use MI Paste under their removable upper denture for 14 days and instructed to monitor symptoms of comfort, retention, and dry mouth (if applicable). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06406751
Study type Interventional
Source University of Iowa
Contact
Status Enrolling by invitation
Phase N/A
Start date June 2024
Completion date May 2025
View Details
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