Surface Treatment of the Dental Implant on the Osseointegration

Dental Implants Clinical Trial

Official title:

The Effect of Surface Treatment of the Dental Implant on the Osseointegration in Mandibular Posterior Missing Teeth

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05194813
• Other study ID #: Implants2022
• Status: Completed
• Phase: N/A
• Start date: November 1, 2020
• Est. completion date: June 15, 2021

Study information

• Verified date: January 2022
• Source: Alexandria University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Dental implants have become a widely accepted treatment modality for the replacement of missing single or multiple teeth in the recent years. In order to meet patients' needs for shorter treatment times and the necessity of dealing with more challenging clinical situations, implants and implant therapies have undergone continuous improvement to improve the function and longevity of the implants. Recently the constant search for improvements in modern implant have been focused on surface modifications so a new era of surface treatment have been showed up; the chemically modified hydrophilic surfaces.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: June 15, 2021
• Est. primary completion date: June 15, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• Missing mandibular posterior teeth.

• Good oral hygiene (plaque index less than 10 %)

• Good compliance to the treatment.

• Participants are free from local or systemic disease

• Willingness and ability to commit to follow-up placement.

• Adequate bone height and width to accommodate implant placement and sufficient keratinzed mucosa.

• At least 3months after tooth extraction

• Sufficient interocclusal distance

Exclusion criteria

• Presence of persistent and unresolved infection in the implant site

• Parafunctional habits.

• Heavy Smokers.

• Uncontrolled systemic disease that impedes bone healing

Related Conditions & MeSH terms

• Dental Implants

Intervention

Other:
• Aqua alvim CM, neodent implant (Test)
Acqua, Hydrophilic sandblasted, and acid-etched dental implants
• Neoporous alvim CM, neodent implant (Control)
Neoporous, Hydrophilic sandblasted, and acid-etched dental implants

Locations

Country	Name	City	State
Egypt	Alexandria Faculty of Dentistry	Alexandria

Sponsors (1)

Lead Sponsor	Collaborator
Hams Hamed Abdelrahman

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in implant stability	The implant stability measurement was examined at the time of insertion of the implants (primary stability) and 6 months (secondary stability) for the two groups of patients using the resonance Frequency Analysis (RFA) via the Osstell ISQ system	at baseline and 6 months
Primary	Change in bone density	Cone beam Computerized tomography was used to assess bone denisty	at baseline and 6 months
Primary	Change in ridge height	Cone beam Computerized tomography was used to assess ridge height	at baseline and 6 months
Primary	Biochemical assessment of bone formation	Done by measuring of Runt-related transcription factor 2 (RUNX2) as a bone marker by Enzyme-Linked Immunosorbent Assay	at 3 months