Dental Implant Clinical Trial
Official title:
The Effect Of Platelet Rich Fibrin on Implant Stability
The purpose of this study was to evaluate the effects of (Platelet Rich Fibrin) PRF application on implant osseointegration in the early phase of healing.
Objectives:Achieving accelerated implant osseointegration could provide immediate or early
loading of implants. Platelet-rich fibrin (PRF) is widely used to accelerate soft and hard
tissue healing. Activated platelets in PRF release growth factors resulting in cellular
proliferation, collagen synthesis and osteoid production. The aim of this study was to
compare the stability of dental implants inserted with one-stage surgical protocol with or
without PRF application.
Design: Non-randomized, Active Controlled Trial. Material and Methods: Twenty healthy
patients (n=10 test group, n= control group) with adequate alveolar bone, having 2 or more
adjacent missing teeth, extracted at least 6 months ago were included in this study. Minimum
two tapered implants (Ankylosis, DentsplyFriadent) were placed to each patient. After
surgical preparation of implant sockets, PRF that was prepared preoperatively was placed
randomly to one of the sockets (PRF+). Acellular plasma portion of PRF was used to wet the
implant placed into the PRF-coated socket. Resonance frequency measurements were made by
Osstell ISQ after placement of implants, at 1 week and one month postoperatively.
Key Words: Dental implant stability, Platelet Rich Fibrin, Resonance frequency analysis
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Health Services Research
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