Comparison of Articaine and Prilocaine for Extraction of Maxillary Teeth

Dental Extraction Clinical Trial

Official title: Does Articaine, Rather Than Prilocaine, Increase the Success Rate of Anaesthesia for Extraction of Maxillary Teeth

Status Completed

Clinical Trial Summary

Ninety-five patients, aged between 16 and 70 years old, were included in this study. Patients were divided into two groups. Group one received Articaine 4% with 1:00.000 Adrenalines. Group two received Prilocaine with 3% Felypressin (0.03 I.U. per ml). Onset time of anaesthesia was objectively evaluated by using electronic pulp testing.

Clinical Trial Description

85 patients in this study had successful local anaesthetic followed by extraction within the study duration time (10 minutes). However, there were six patients with failure anaesthesia (5 in prilocaine group and 1 in articaine group). By application Person's Chi-square test (x2), there were no significant differences in the number of the episodes of the anaesthetic success between articaine and prilocaine groups at time intervals (P-value = 0.5). T- test showed there have been no important variations within the mean onset time of anaesthesia for articaine and prilocaine buccal infiltrations (P-value =0.1). ;

Related Conditions & MeSH terms

• Dental Extraction
• Maxillary Teeth
• Overcoming the Failure of Anaesthesia

• NCT number: NCT04236115
• Study type: Interventional
• Source: Taibah University
• Status: Completed
• Phase: Phase 4
• Start date: September 20, 2017
• Completion date: June 20, 2018