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Dental Enamel Hypoplasia clinical trials

View clinical trials related to Dental Enamel Hypoplasia.

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NCT ID: NCT06461143 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

Intraosseous Local Anesthesia System in Children With Molar Incisor Hypomineralization

Start date: June 24, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare in effectiveness of intraosseous anesthesia and inferior alveolar block anesthesia in children with molar incisor hypomineralization (MIH). The main question it aims to answer are: - Is intraosseous anesthesia is more effective in pain control when restoring hypersensitive teeth with MIH?

NCT ID: NCT06426108 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

Interventions to Control Hypersensitivity Pain in Teeth With Insisive Molar Hypomineralization

LBIARHMI
Start date: July 1, 2024
Phase: Early Phase 1
Study type: Interventional

Molar incisor hypomineralization (MIH) manifests as a qualitative, demarcated defect in tooth enamel of systemic origin, predominantly affecting one or more permanent first molars, and potentially extending to the incisors. One significant challenge in managing this enamel anomaly is hypersensitivity, leading to discomfort and pain in affected patients. Low-intensity laser therapy, alone or combined with other modalities, appears promising in alleviating pain associated with MIH. This study aims to assess the efficacy of low-intensity laser therapy using varied parameters, in conjunction with a remineralizing agent, for pain management in children with molar incisor hypomineralization. Participants aged 6 to 12 years will be recruited, with a total of 88 teeth diagnosed with MIH, presenting a sensitivity score ≤3 on the Visual Analog Scale (VAS) and a score ≤1 on the Schiff Cold Air Sensitivity Scale (SCASS). The teeth will be randomly assigned to one of four groups (n=22 each): Group I (GI): L-1J + VF, Group II (GII): L-1J + VP, Group III (GIII): L-2J + VF, and Group IV (GIV): L-2J + VP. Here, 'L' denotes low-intensity laser application at different parameters (1J and 2J), combined with either fluoride varnish (VF) or a placebo varnish (VP). Interventions and assessments will be conducted initially, after 48 hours, and at 1 and 2 weeks post-treatment. Patients will undergo re-evaluation at 2, 4, 8, and 12 weeks following interventions. Statistical analyses will be performed with a 95% confidence level (α = 0.05).

NCT ID: NCT06342089 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

Association Between Molar Incisor Hypomineralization And Type I Diabetes Milletus.

Start date: September 2024
Phase:
Study type: Observational

- Determine the association between molar incisor hypomineralization and type I diabetes millutes, its severity and treatment need via clinical examination of children with type I diabetes millutes . - Teeth will be cleaned gently using gauze and wet with saliva during examination. A disposable diagnostic set (mirror, probe) will be used for each patient where mirrors will be used for proper visualization especially for maxillary teeth. - Blunt explorers will be used to aid in tactile sensation if needed, as during the differentiation between rough and smooth enamel edges and/or during the inspection of the caries extent if it exists. No diagnostic radiographs will be taken. - The severity and treatment needs of each case with MIH will be recorded in patient's chart. - The results of the study will be regularly monitored by the supervisors who will have full access to these results.

NCT ID: NCT06330272 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

Accuracy of Spectrophotometry in Hypomineralized Lesions Treated With CPP-ACPF Dental Mousse: Clinical Study

ASHLTDMCS
Start date: May 2024
Phase: N/A
Study type: Interventional

MIH is a condition with considerable prevalence in the child population. This structural defect, represented by a change in the color of the enamel, can be accompanied by structural loss and great sensitivity. Remineralizing agents have been used to strengthen compromised enamel. The objective of the study will be to measure the accuracy of a spectrophotometer (VITA Easyshade V) in determining the mineralization of IMH lesions by a CPP-ACPF dental mousse.

NCT ID: NCT06180369 Not yet recruiting - Clinical trials for Molar-Incisor Hypomineralization

Clinical Efficacies of Different Agents in Molar-Incisor Hypomineralization

Start date: December 2023
Phase: N/A
Study type: Interventional

This study aims to assess the clinical effectiveness of GC Fuji Triage ® (GC America Inc., Alsip, Illinois) and BeutiSealant (Shofu, Kyoto, Japan) in children aged 8-13 with multiple molars affected by Molar-Incisor Hypomineralization (MIH). The comparison focuses on permanent first molars affected by MIH.

NCT ID: NCT06165055 Not yet recruiting - Clinical trials for Molar-Incisor Hypomineralization

Single Gene Polymorphisms Associated With Molar-Incisor Hypomineralization

Start date: December 2023
Phase:
Study type: Observational

The genetic factors associated with Molar-Incisor Hypomineralization (MIH), a dental condition affecting permanent molars in individuals aged 8-13. Buccal swab samples collected from 90 MIH-affected participants and 90 systemically healthy controls. The goal is to identify potential genetic markers contributing to the etiology of MIH, shedding light on previously unexplored aspects of genetic susceptibility.

NCT ID: NCT06165042 Not yet recruiting - Clinical trials for Molar-Incisor Hypomineralisation

Silver Diamine Fluoride in Molar-Incisor Hypomineralisation

Start date: December 2023
Phase: N/A
Study type: Interventional

The objective of this study is to assess the efficacy of silver diamine fluoride application in molars affected by molar-incisor hypomineralization. Additionally, the study aims to evaluate the effectiveness of the combined application of silver diamine fluoride, commonly used for dentin hypersensitivity, with a glass hybrid restorative system. The goal is to mitigate sensitivity and improve chewing functions in teeth affected by molar-incisor hypomineralization.

NCT ID: NCT06154733 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

HYPERSENSITIVITY IN MOLAR INCISOR HYPOMINERALISATION USING LOW LEVEL LASER IN CHILDREN

Start date: January 2024
Phase: N/A
Study type: Interventional

Molar Incisor Hypomineralisation (MIH) is a qualitative defect of enamel that shows asymmetrically involvement of one to four on first permanent molars (FPM) with or without incisor teeth involvement. Hypersensitivity is one of the biggest challenges in the treatment of MIH. A sample of children having a first permanent molar erupted with MIH and suffering of dentin hypersensitivity (DH). All selected 45 first permanent molars will be randomly equally allocated into three groups. DH will be evaluated after the treatments. The primary outcome of this study is change in pain/sensitivity, when evaluated through a Visual Analogue Scale. OHRQoL will be also assessed for all children through the child perceptions questionnaire (CPQ8-10).

NCT ID: NCT06137391 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

Effectiveness of Pulpotomy in Carious First Permanent Molar

Start date: January 2024
Phase: N/A
Study type: Interventional

Pediatric dentists frequently encounter deeply carious young permanent first molars (PFM) with Molar Incisor Hypomineralisation (MIH). Pulpal status of affected PFM was found to be different from that of unaffected PFMs which consequently might influence the pulpal response after vital pulp therapy. The aim of this study is to evaluate the clinical and radiographic effectiveness of partial removal of pulp in deeply carious symptomatic PFM affected with MIH over 24 months.

NCT ID: NCT06135272 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

Evaluation of Three Different Minimally Invasive Techniques for Management of Enamel Opacities in Patients With Molar Incisor Hypomineralization "Randomized Controlled Clinical Trial"

Start date: December 1, 2023
Phase: Phase 4
Study type: Interventional

The controlled clinical trial will be done to evaluate Resin infiltration, Resin modified glass ionomer varnish and Light cured giomer varnish as minimally invasive techniques for management of enamel opacities of patients with molar incisor hypomineralization. Variation in mineral density of the enamel opacity , ,Hypersensitivity, Color change of the enamel opacity, Quality of life of the patient, Parent Satisfaction will be evaluated preoperatively and at 1, 3,6,12 and 18 months of follow up.