Development of a Novel Anti-caries Chewing Gum

Status Not yet recruiting

Clinical Trial Summary

This research study is designed to evaluate the chewing gum's ability to modulate the oral microbiome in human participants, in addition to its safety.

Clinical Trial Description

The goal of this project is to develop a pre-biotic chewing gum that is designed to promote a healthy oral microbiome. The gum will contain compounds that will: a) be unable to be converted to acids; b) target the cariogenic S. mutans population; c) promote the stability of a healthy environment by modulating plaque pH via base-generating compounds; d) promote tooth remineralization by increasing saliva flow and by addition of calcium phosphate. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05946473
Study type	Interventional
Source	University of Toronto
Contact
Status	Not yet recruiting
Phase	N/A
Start date	July 2023
Completion date	April 2024

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