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Clinical Trial Summary

The main aim of the study is to currently define the prevalence of celiac disease (CD) in children aged 5-10 years in 2 Italian cities (Ancona and Verona). The screening protocol is based on a 1st line genetic test (searche of HLA DQ2/DQ8 genotypes) followed by a serological diagnosis (IgA TTG and IgG DGP).


Clinical Trial Description

All scholar children aged 5-10 years living in the cities of Ancona and Verona will be invited to partecipate. Children enrolled will be investigated as follows: 1. HLA DQ2/DQ8 genotyping (by a rapid test) 2. In children genetically predisposed to CD serological investigations will be performed (both IgA TTG and IgG DGP antibodies) 3. The overall population will be evaluated for the prevalence and severity of dental caries (by using the DMFT/dmft index) ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04867863
Study type Observational
Source Università Politecnica delle Marche
Contact
Status Completed
Phase
Start date May 2015
Completion date June 2018

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