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Silver Diamine Fluoride for Caries Prevention in Removable Partial Dentures Wearers

Dental Caries Clinical Trial

Official title:
Randomized Double-blind Placebo-controlled Trial of Silver Diamine Fluoride for Caries Prevention in Removable Partial Dentures Wearers

Clinical Trial Summary

This study measures and compares the effect of silver diamine fluoride (SDF) on caries increment in removable partial denture wearers. Half of the participants will SDF and while the other half will receive placebo.

Clinical Trial Description

Removable partial dentures are commonly constructed to replace missing teeth. It is observed that removable partial denture wearers are susceptible to dental caries.

The mode of action of silver diamine fluoride on caries prevention is dual: fluoride ions interact synergistically with silver to react with hydroxyapatite to form fluorapatite, and silver is bactericidal by reacting with the thiol groups of the amino and nucleic acids that halt the metabolic and reproductive functions of the cariogenic bacteria. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03185104
Study type Interventional
Source The University of Hong Kong
Contact
Status Active, not recruiting
Phase N/A
Start date November 1, 2013
Completion date December 31, 2017
View Details
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