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Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes

Dental Caries Clinical Trial

Official title:
Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes

Clinical Trial Summary

Fluoride toothpaste has been associated not only with declining dental caries prevalence but also with an increase in dental fluorosis. In the balance of benefits/risks of fluoride toothpaste use, the purpose of this study is to evaluate the availability of fluoride concentration in the mouth (biofilm fuild), as an indicator of fluoride benefits (anticaries effect), and the fluoride concentration in urine, as an indicator of fluoride absorption from ingested toothpastes (with potential to cause dental fluorosis), in a sample of young Brazilian children using toothpaste formulations representative of those available and most used by this age-group.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01589991
Study type Interventional
Source University of Campinas, Brazil
Contact
Status Completed
Phase Phase 1
Start date January 2011
Completion date July 2013
View Details
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