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NCT01569165 Clinical Trial

Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH

Dental Caries Clinical Trial

Official title:
Effect of Water Rinsing After APF Application on Dental Plaque Acidogenicity

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01569165
Other study ID # 89629
Secondary ID
Status Completed
Phase N/A
First received March 29, 2012
Last updated March 30, 2012
Start date February 2011
Est. completion date November 2011

Study information
Verified date March 2012
Source Mashhad University of Medical Sciences
Contact n/a
Is FDA regulated No
Health authority Iran: Ethics Committee
Study type Interventional

Clinical Trial Summary

The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.

Recruitment information / eligibility
Status Completed
Enrollment 25
Est. completion date November 2011
Est. primary completion date October 2011
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 21 Years to 29 Years
Eligibility Inclusion Criteria:

- healthy people (Without any systemic disease)

- normal unstimulated salivary rate

Exclusion Criteria:

- Active dental caries

- taking any medication with any effect on saliva rate

- taking antibiotic (or antibacterial mouth rinses) during last 4 weeks

- usig fluoride mouth rinses during last 2 weeks.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Intervention

Procedure:
• cleansing teeth after topical fluoride therapy
washing with water 0, 15 or 30 min after APF treatment or cleansing teeth with cotton roll immediately following APF treatment.

Locations
Country Name City State
Iran, Islamic Republic of Dental School - Mashhad University of Medical Siences Mashhad Khorasan Razavi

Sponsors (1)
Lead Sponsor Collaborator
Mashhad University of Medical Sciences

Country where clinical trial is conducted

Iran, Islamic Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary dental plaque PH the pH of 48-hour dental plaque was measured using plaque sampling method before (baseline pH) and after sucrose challenge at 5, 10,15,20,30 minutes No
Secondary maximum pH drop 5,10,15,20 and 30 min after sucrose chalenge No
Secondary pH recovery time time for returning to the baseline pH within 30 min after sucrose challenge No
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