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Dental Caries Extending to Pulp clinical trials

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NCT ID: NCT06016218 Completed - Clinical trials for Dental Implant Failed

Effect of Local Application of Simvastatin Versus Bone Powder on Implant Bone Changes

Start date: January 5, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This study is conducted A- To investigate that PRF loaded with osteopromotive pharmacological drug can be a great aid in implant rehabilitation, and whether it could be a replacement for the other high price bone graft materials or not. This will be done through: 1. Measuring bone changes around the implant by cone beam 2. Measuring change in bone density around the implants B- Evaluate the effect of statins on osteoblasts activity and expression of various osteogenic products in vitro.

NCT ID: NCT03735069 Completed - Clinical trials for Molar Incisor Hypomineralization

Vital Pulp Therapy in Carious Teeth With Hypomineralization

Start date: September 12, 2017
Phase: N/A
Study type: Interventional

Vital pulp therapy (VPT) is a general term for multiple procedures (indirect pulp cap, direct pulp cap and pulpotomy) all directed toward preserving pulp vitality and enable complete root development in immature teeth. The aim of this study is to evaluate the clinical, radiographic and histologic (if any teeth later are doomed for extraction for orthodontic or other reasons) success rate of VPT on treating cariously exposed permanent teeth with developmental defects of enamel. This will be a a prospective case series study including children between 6-16 years old having tooth with enamel hypomineralization defect with deep caries, restorable teeth , and no signs of infection. The teeth will be followed up both clinically and radiographically for 1 year after treatment. It is expected that the teeth will maintain vitality with resolution of symptoms (if present) and completion of root development in immature teeth after vital pulp therapy.

NCT ID: NCT03410134 Recruiting - Clinical trials for Pulp Disease, Dental

Assessment of Vital Pulp Therapy in Permanent Molars

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the long term clinical performance of vital pulp therapy of young permanent teeth with irreversible pulpitis

NCT ID: NCT03403985 Active, not recruiting - Dental Pulp Capping Clinical Trials

Long-term Evaluation of Direct Pulp Capping

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

Calcium hydroxide and mineral trioxide aggregate have been used in vital pulp therapy with variable outcomes recorded by different study. They will be compared when used for direct pulp capping in cariously exposed mature permanent teeth.

NCT ID: NCT03254290 Not yet recruiting - Clinical trials for Dental Caries Extending to Pulp

Color Stability of NeoMTA Pulpotomized Primary Teeth

Start date: October 1, 2017
Phase: Early Phase 1
Study type: Interventional

This randomized control study will use 15 pediatric subjects selected from the patient population in the pediatric dental clinic at Children's Medical Center Dental Clinic (CMC Dental Clinic). The study will use a within-subject control design whereby one tooth will be treated with a pulpotomy using the new formulation of MTA (NeoMTA Plus, Avalon Biomed Inc., Bradenton, FL, USA) and restored with a multi-surface composite, and the other tooth with a formocresol pulpotomy and restored with a multi-surface composite; thus, approximately 15 teeth will be treated for each treatment group. The specific treated tooth will be randomized as to which side will receive the MTA or formocresol using sealed, opaque envelopes. Approximately 15 subjects will be needed for the study in order to elicit any significant findings as demonstrated by a power analysis.