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Dengue Haemorrhagic Fever clinical trials

View clinical trials related to Dengue Haemorrhagic Fever.

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NCT ID: NCT02827162 Completed - Dengue Fever Clinical Trials

Association of Host Genetics With Vaccine Efficacy and Study of Immune Correlates of Risk From a Tetravalent Dengue Vaccine

Start date: March 29, 2016
Phase:
Study type: Observational

Primary objectives: - To assess how dengue vaccine efficacy varies across participant subgroups regarding polymorphism in human leukocyte antigen (HLA) alleles of interest. - To assess the association between HLA alleles and, serotype-specific neutralization antibody titers and summary neutralization measure in the vaccine and placebo groups. - To assess the association between the polymorphism in HLA alleles of interest and susceptibility to Dengue fever and Dengue Haemorrhagic fever. Secondary objectives: - To assess whether dengue serotype-specific neutralizing antibody titers and associated summary neutralization measure at 28 days post-dose 3 are related to the rate of occurrence of symptomatic Virologically-confirmed dengue infection after post-dose 3 - To evaluate whether the dengue serotype-specific neutralizing antibody and associated summary neutralization measure at 28 days post-dose 3 are related to the level of vaccine efficacy against dengue viruses after post-dose 3.

NCT ID: NCT01601613 Completed - Clinical trials for Acquired Bleeding Disorder

Activated Recombinant Human Factor VII in Patients With Dengue Haemorrhagic Fever

Start date: July 2001
Phase: Phase 2
Study type: Interventional

This trial is conducted in Asia. The aim of this is to investigate the efficacy and safety of activated recombinant human factor VII (rFVIIa) in achieving haemostasis in patients with Dengue haemorrhagic fever (DHF).