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NCT00688389 Clinical Trial

Investigation of the Immuno-regulation and Viral Hepatitis Among Patients With or After Dengue Fever Infection

Dengue Fever Clinical Trial

Official title:
Follow-up the Health Condition , Investigation of the Immuno-regulation , and the Study for Interaction of Viral Hepatitis--- Among Patients With or After Dengue Fever Infection

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00688389
Other study ID # KMUH-IRB-960195_1
Secondary ID CB9615
Status Recruiting
Phase
First received
Last updated
Start date July 2007
Est. completion date December 31, 2020

Study information
Verified date February 2019
Source Kaohsiung Medical University Chung-Ho Memorial Hospital
Contact Jih-Jin Tsai, MD
Phone 886-7-312-1101
Email jijits@cc.kmu.edu.tw
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The study will collect the blood samples from 350 healthy persons and 350 persons infected with dengue fever.

Description:

Research has showed that CLEC5A interacts with dengue virion directly, and is responsible for dengue virus (DV)-induced DAP12 phosphorylation. Data suggests that CLEC5A is a potential therapeutic target for dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS). This project will study the genes of CLEC5A, Mannose receptor, DC-SIGN, NALP, decoy receptor 3 (DcR3), Toll-like receptors(TLRs), and (Nod)-like receptors (NLRs) for both DF and DHF groups. In addition, serum level of decoy receptor 3 (DcR3) will be tested. The study will collect the blood samples from 350 healthy persons and 350 persons infected with dengue fever.

Recruitment information / eligibility
Status Recruiting
Enrollment 700
Est. completion date December 31, 2020
Est. primary completion date December 31, 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- Clinical diagnosis of Dengue fever

Exclusion Criteria:

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• case/control
case: infected dengue fever people control:healthy people

Locations
Country Name City State
Taiwan Kaoshing Medical University Chung-Ho Memorial Hospital Kaohsiung

Sponsors (2)
Lead Sponsor Collaborator
Kaohsiung Medical University Chung-Ho Memorial Hospital Centers for Disease Control and Prevention

Country where clinical trial is conducted

Taiwan, 

Outcome
Type Measure Description Time frame Safety issue
Primary ??????????????,????????????????? ??20 c.c ??????????????,????????????????? 2007/7/1
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