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Investigation of the Immuno-regulation and Viral Hepatitis Among Patients With or After Dengue Fever Infection

Dengue Fever Clinical Trial

Official title:
Follow-up the Health Condition , Investigation of the Immuno-regulation , and the Study for Interaction of Viral Hepatitis--- Among Patients With or After Dengue Fever Infection

Clinical Trial Summary

The study will collect the blood samples from 350 healthy persons and 350 persons infected with dengue fever.

Clinical Trial Description

Research has showed that CLEC5A interacts with dengue virion directly, and is responsible for dengue virus (DV)-induced DAP12 phosphorylation. Data suggests that CLEC5A is a potential therapeutic target for dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS). This project will study the genes of CLEC5A, Mannose receptor, DC-SIGN, NALP, decoy receptor 3 (DcR3), Toll-like receptors(TLRs), and (Nod)-like receptors (NLRs) for both DF and DHF groups. In addition, serum level of decoy receptor 3 (DcR3) will be tested. The study will collect the blood samples from 350 healthy persons and 350 persons infected with dengue fever. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00688389
Study type Observational
Source Kaohsiung Medical University Chung-Ho Memorial Hospital
Contact Jih-Jin Tsai, MD
Phone 886-7-312-1101
Email jijits@cc.kmu.edu.tw
Status Recruiting
Phase
Start date July 2007
Completion date December 31, 2020
View Details
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