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Dementia, Vascular clinical trials

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NCT ID: NCT00209456 Completed - Vascular Dementia Clinical Trials

Dopamine Transporter Scintigraphy Imaging (DAT-Imaging) in Patients With Lewy Body Dementia

Start date: November 2003
Phase: Phase 3
Study type: Interventional

The study is designed to determine the diagnostic efficacy of the visual assessment of SPECT scans in differentiating between probable dementia with Lewy Bodies (DLB) and non-DLB dementia subjects determined by the clinical diagnosis of an independent expert consensus panel used as the standard of truth.

NCT ID: NCT00174382 Terminated - Dementia, Vascular Clinical Trials

Vaspect Study - An Open-Label Trial Of Donepezil in Vascular and Mixed Dementia

Start date: June 2005
Phase: Phase 3
Study type: Interventional

To document effectiveness, safety, and tolerability of donepezil in patients with mixed AD/VaD, and to further document the effectiveness, safety, and tolerability of donepezil in patients with VaD. The effects of donepezil on executive functioning, behavior, general cognition, ADLs and global functioning will be assessed.

NCT ID: NCT00172900 Recruiting - Alzheimer's Disease Clinical Trials

MRS and DTI of White Matter in Alzheimer's Disease

Start date: June 2005
Phase: N/A
Study type: Observational

The white matter change of the Alzheimer's disease could be studied by diffusion tensor image and MR spectroscopy to see the microstructral and biochemical change.

NCT ID: NCT00165763 Completed - Vascular Dementia Clinical Trials

Efficacy and Safety of Donepezil Hydrochloride (Aricept) in Vascular Dementia

Start date: September 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to examine the efficacy and safety of cholinesterase inhibitor (donepezil hydrochloride) Aricept in patients with vascular dementia (VaD).

NCT ID: NCT00165737 Completed - Dementia, Vascular Clinical Trials

Donepezil Hydrochloride (E2020) in Dementia Associated With Cerebrovascular Disease

Start date: March 2003
Phase: Phase 3
Study type: Interventional

Twenty-four week, prospective, randomized, double-blind, placebo-controlled, parallel-group study.

NCT ID: NCT00147693 Completed - Alzheimer Disease Clinical Trials

Systematic Care for Informal Caregivers of Dementia Patients: An Efficient Approach?

Start date: June 2005
Phase: N/A
Study type: Interventional

The objective is to ascertain the potential efficiency of a systematic care programme for caregivers of dementia patients. The research questions are: - What are the costs and benefits of the Systematic Care Programme - Dementia (SCP-Dementia), as compared with usual care? - What are the effects on the quality of life of patients and informal caregivers (spouse, relative), as compared with usual care?

NCT ID: NCT00130338 Completed - Vascular Dementia Clinical Trials

Rivastigmine Capsules in Patients With Probable Vascular Dementia

Start date: February 2002
Phase: Phase 3
Study type: Interventional

The goal of this research study is to evaluate, in the open-label extension phase, the effectiveness, tolerability and safety of rivastigmine capsules in males and females between the ages of 50 and 85 years old with probable vascular dementia.

NCT ID: NCT00099216 Completed - Vascular Dementia Clinical Trials

Efficacy and Safety of Rivastigmine Capsules in Patients With Probable Vascular Dementia

Start date: August 2001
Phase: Phase 3
Study type: Interventional

The goal of this research study is to evaluate the effectiveness, tolerability and safety of rivastigmine capsules in males and females between the ages of 50 and 85 years old with probable vascular dementia.

NCT ID: NCT00035191 Completed - Dementia, Vascular Clinical Trials

A Placebo-controlled Trial to Evaluate the Safety and Efficacy of Galantamine in the Treatment of Vascular Dementia

Start date: October 2001
Phase: Phase 3
Study type: Interventional

This is a trial to evaluate the safety and effectiveness of galantamine in patients with dementia secondary to blood vessel disease in the brain.

NCT ID: NCT00009204 Completed - Alzheimer Disease Clinical Trials

Serotonergic Pharmacotherapy for Agitation of Dementia

SPAD
Start date: September 1995
Phase: Phase 3
Study type: Interventional

This study is a randomized, double-blind, placebo-controlled, fixed dose study currently being conducted on two geropsychiatric units at Western Psychiatric Institute and Clinic. It seeks to evaluate the short-term safety and efficacy of citalopram and perphenazine in the treatment of 112 patients suffering from behavioral disturbances associated with dementia. Findings from this research may directly lead to improved acute pharmacotherapy for psychosis and behavioral problems in patients diagnosed with dementia. Improved treatment of behavioral complications with reduced side effects would reduce excess disability in patients diagnosed with dementia, allowing them to be maintained in the community for greater periods of time.