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NCT02366299 Clinical Trial

Comparison of Dexmedetomidine and Propofol on the Delirium and Neuroinflammation in Patients With SIRS.

Delirium Clinical Trial

Official title:
Comparison of Sedative Effects of Dexmedetomidine and Propofol on the Clinical Course of Delirium and Neuroinflammation in Patients With SIRS.

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT02366299
Other study ID # D-P-SIRS-220115
Secondary ID
Status Withdrawn
Phase Phase 4
First received
Last updated
Start date February 2015
Est. completion date December 2018

Study information
Verified date August 2019
Source Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Assessment of sedative effects of dexmedetomidine and propofol on the clinical course of delirium and neuroinflammation in patients with SIRS using CAM-ICU scale and protein S100b in serum.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date December 2018
Est. primary completion date December 2018
Accepts healthy volunteers No
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- presence of delirium

Exclusion Criteria:

- presence of Alzheimer's disease

- any mental disorder

- presence of cancer

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Dexmedetomidine
Treatment of delirium by dexmedetomidine i.v. infusion
• Propofol
Treatment of delirium by Propofol i.v. infusion

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy

Outcome
Type Measure Description Time frame Safety issue
Primary CAM-ICU scale up to 5 days
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