Delirium Clinical Trial
Official title:
ICU Delirium: a One-week Snapshot of Burden Across the Eastern UK Region
ICU delirium negatively impacts on patient outcomes, as well as on resources and clinical
workflow of the ICU. Effective healthcare resource planning requires reliable (i.e.,
multicentre) data that can inform on both of these.
The purpose of this study was to determine the impact of ICU delirium in terms of both
patients and beds. The study was carried out prospectively, over a one-week period, at adult
ICUs comprising the Norfolk, Suffolk, and Cambridgeshire Critical Care Network (NSC CCN).
Previous delirium prevalence research has been carried out at single sites and yielded
highly variable results (between 3-87%). Reliable multisite data can be obtained
cost-effectively using a point-prevalence ("snapshot") approach.
Purpose: to obtain reliable data informing on prevalence of ICU delirium, in terms of both
patients and beds, across the eastern UK region.
Design and Setting: this one-week observational prospective cohort study was carried out
between June 25, 2012 (start of ICU day shift) to July 01, 2012 (end of night shift). Nine
ICUs comprising the Norfolk, Suffolk, and Cambridgeshire Critical Care Network (NSC CCN)
took part. Cambridgeshire 2 Research Ethics Committee approved the study (REC reference:
10/H0308/116) and waived the need for informed consent.
Patients and procedure: All adults treated over the study week at participating ICUs were
considered eligible for inclusion. Delirium screening was carried out by patients' direct
care clinicians using the Confusion Assessment Method for the ICU (CAM-ICU). All sites used
this tool as part of their routine clinical practice and had delirium management guidelines
in place at the time of the study. Patients who screened positive for delirium were treated
according to local hospital practice.
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Time Perspective: Prospective
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