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Delirium clinical trials

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NCT ID: NCT04969523 Not yet recruiting - Clinical trials for Postoperative Delirium

Effect of Es-ketamine on Postoperative Delirium Among Old Patients With Lobectomy

Start date: July 31, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is the efficiency of es-ketamine on postoperative delirium among old patients with elective lobectomy

NCT ID: NCT04962815 Recruiting - Delirium Clinical Trials

Ceribell Delirium Data Collection Study

Start date: November 10, 2021
Phase:
Study type: Observational [Patient Registry]

This study is designed as a prospective, non-randomized, observational clinical study. The study will collect clinical and rrEEG (Ceribell EEG) data when monitoring subjects for delirium subtypes. EEG and clinical data will be collected for the development of future software algorithms to assess the presence and severity of delirium.

NCT ID: NCT04957238 Recruiting - Critically Ill Clinical Trials

Physical Restraints in Intensive Care Unit Patients

ARBORéa
Start date: May 18, 2022
Phase: N/A
Study type: Interventional

The use of physical restraints is common practice in Intensive Care Units (ICU). This medically prescribed procedure requires full attention of medical and paramedical teams for its implementation, monitoring and ending, as a major restriction of patients' individual freedom. French highest authority for health has defined, for geriatrics and psychiatric units, ten criteria of good practice for physical restraints' use. Routine practice reports critically ill patients' safety as main reason of use. This decision, often left to the sole discretion of nurses, varies according to their own representation of this risk, and depends on several factors: seniority in ICU, nurse to patient ratio and personal workload. In order to reduce practices subjectivity and heterogeneity, we have developed a decision-making tool for physical restraints implementation. This tool is based on objective scales used on a daily basis concerning neurological status (Richmond Agitation-Sedation Scale (RASS) and Confusion Assessment Method for the ICU (CAM-ICU)). Disorientation or delirium can lead to severe incidents by promoting accidental removing of important devices such as arterial of venous line, drains among others. However, physical restraints are recognized as a major cause of delirium and agitation. Critically ill patients require rigorous evaluation of organ dysfunctions necessitating adequate invasive equipments, with associated risks of unexpected removal or alteration. Such events could urge caregivers to use physical restraints. Based on recent literature, about a third of ICU patients are restrained, and accidental deconditioning is mainly observed within these particular patients. In addition, three categories of patients have been defined according to the invasive nature of their equipment and therefore according to the risk associated with an unexpected withdrawal. Finally, presence of patient's family and their adherence to its surveillance were also implemented into the tool. Main study objective is to jointly investigate effectiveness and tolerance of a decision-making tool guiding physical restraints use in ICU patients.

NCT ID: NCT04955249 Recruiting - Elderly Clinical Trials

Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery

Start date: November 18, 2021
Phase: Phase 4
Study type: Interventional

Delirium is common in the elderly after hip fracture surgery, and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after hip fracture surgery, dexmedetomidine supplemented analgesia can reduce the incidence of delirium and improve the long-term outcomes.

NCT ID: NCT04954261 Withdrawn - Delirium Clinical Trials

Delirium Detection in Pediatric Intensive Care Unit Through a French Translation of the CAPD : a French Monocentric Observational Study

DeliReP
Start date: December 6, 2018
Phase:
Study type: Observational

The purpose of this study is to introduce delirium detection and try to determine the prevalence of delirium in Pediatric Intensive Care Unit (PICU) using a validated tool : the Cornell Assessment of Pediatric Delirium (CAPD) for every patient twice a day.

NCT ID: NCT04953767 Recruiting - Delirium Clinical Trials

The Circadian Rhythm of ICU Patients With Acute Myocardial Infraction and the Effect of Light Therapy

Start date: May 12, 2021
Phase: N/A
Study type: Interventional

By using subjective and objective measurements, the investigators monitor the change of circadian rhythm in Intensive Care Unit (ICU) patients with acute myocardial infarction and the effect of light therapy.

NCT ID: NCT04950738 Not yet recruiting - Delirium Clinical Trials

The Effectiveness of Acupuncture for Complications in Critically Ill Patients

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

Introduction: Intensive care unit (ICU) is a special department in the health care facility. Although with high development of modern medicine nowadays, the average mortality rate in ICU is still around 7 to 20 %. There are a few tricky problems that intensivists and ICU nurses faced very often, including ICU delirium, arrhythmia and poor digestion problem that will all affect the mortality and morbidity rate of critical care patients. Methods: A randomized control trial will examine the effect of press tack acupuncture vs. press tack placebos. The patients will be randomly divided (1:1) into one of two groups. A total of 80 ICU patients will have to meet the following criteria: age 20-90, newly ICU admission(<48 hours), APACHE score <30, one or no inotropic medicine use, FiO2< 60%. Three interventions will be given in each group. The main outcomes will be the incidence of arrhythmia, delirium, and poor digestion and the severity of pain. We will also record ICU mortality, ICU stays and hospital days.

NCT ID: NCT04947761 Recruiting - Clinical trials for Postoperative Delirium

Modified Tian Wang Bu Xin Dan Hydrogel Patch in Preventing Postoperative Delirium in Elderly Patients

Start date: July 13, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether preoperative administration of Modified Tian Wang Bu Xin Dan Hydrogel Patch prevents the incidence of postoperative delirium in elderly patients undergoing major surgery.

NCT ID: NCT04943939 Recruiting - Clinical trials for Postoperative Delirium

Correlation of Electroencephalogram With Postoperative Delirium During Cardiac Surgery

Start date: July 1, 2020
Phase:
Study type: Observational

The purpose of this study is to explore characteristic changes of EEG epileptiform discharges in patients under CPB and correlation with POD

NCT ID: NCT04937400 Recruiting - Delirium Clinical Trials

Delirium in Children Undergoing Stem Cell Transplantation

Start date: July 12, 2021
Phase:
Study type: Observational

Children undergoing stem cell transplants are at risk for delirium, a temporary change in thinking and behavior. This study will define delirium rates, risk factors, and outcomes. Our eventual goal is to reduce delirium in this population.