Effect of Percutaneous Acupoint Electrical Stimulation on Delirium

Status Recruiting

Clinical Trial Summary

This study is a multicenter, prospective, randomized controlled clinical trial that aims to observe the impact of Transcutaneous Electrical Acupoint Stimulation (TEAS) on plasma TK/MMP3 in a randomized controlled setting. The intervention group received percutaneous acupoint electrical stimulation, whereas the control group underwent conventional treatment. The primary objective is to enhance the management of postoperative delirium, specifically focusing on the occurrence and severity of delirium following thoracoscopic pulmonary resection. Additionally, various perioperative inflammatory markers, cognitive function, recovery quality, pain levels, anxiety, sleep patterns, postoperative complications, and overall hospital stay duration were monitored to elucidate the mechanisms through which percutaneous acupoint electrical stimulation improves postoperative delirium.

Clinical Trial Description

Transcutaneous Electrical Acupoint Stimulation (TEAS) is a treatment method that combines acupuncture point theory of traditional Chinese medicine with physical electrical stimulation techniques. It achieves the purpose of acupoint stimulation by applying a weak current to a specific part. Compared with traditional acupuncture, TEAS has the advantages of non-invasiveness, safety, portability and adjustability. Intraoperative acupoint electrical stimulation has no effect on operation and monitoring. This multicenter, prospective, randomized controlled clinical trial aims to investigate the impact of Transcutaneous Electrical Acupoint Stimulation (TEAS) on postoperative delirium following thoracoscopic pulmonary resection. The study design involves the randomized allocation of participants into two groups: an intervention group receiving percutaneous acupoint electrical stimulation and a control group undergoing standard postoperative care. The intervention protocol includes the precise selection of acupoints for TEAS application, parameters for electrical stimulation, frequency of treatments, and duration of intervention sessions. Patients in the control group will receive conventional postoperative management without TEAS. Outcome measures will assess plasma TK/MMP3 levels, incidence and severity of postoperative delirium, perioperative inflammatory markers, cognitive function, pain levels, anxiety, sleep patterns, postoperative complications, recovery quality, and hospital stay duration. Statistical analysis will employ appropriate methods to evaluate the effectiveness of TEAS in managing postoperative delirium. Overall, this clinical trial seeks to contribute to the understanding of how TEAS may improve postoperative delirium management and patient outcomes following thoracoscopic pulmonary resection. The Detailed Description provides a comprehensive overview of the study protocol without duplicating information presented elsewhere in the document. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06360549
Study type	Interventional
Source	Tongji Hospital
Contact	Xiao Ran, phd
Phone	15926207366
Email	ranxiao1001@tjh.tjmu.edu.cn
Status	Recruiting
Phase	N/A
Start date	March 1, 2024
Completion date	June 30, 2025

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT06392308` - The Impact of Smoking on the Prognosis of Elderly Surgical Patients
Completed	`NCT06302517` - Bis Monitoring Effect on Delirium Occurrence and Nursing Quality Improvement Recovering From General Anesthesia	N/A
Recruiting	`NCT06090955` - Modulating Surgery-Induced Blood-Brain Barrier Disruption in Elderly	N/A
Recruiting	`NCT06052397` - Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium
Not yet recruiting	`NCT06107517` - DREAMS-OT Trial: Delirium Reduction Through Early Activation in Motivating and Sleep Promoting Routines: A Randomized Controlled Trial of Occupational Therapy for ICU Patients After Coronary Artery Bypass Graft (CABG) Surgery	N/A
Completed	`NCT04563858` - Polish Validation 4AT Tool
Completed	`NCT06268119` - Effectiveness of Delirium Care Protocol After Cardiac Surgery	N/A
Not yet recruiting	`NCT06268080` - Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery	N/A
Completed	`NCT06187389` - Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Recruiting	`NCT01283412` - Dexmedetomidine on Postoperative Delirium and Quality of Recovery in Geriatric Patients	Phase 3
Recruiting	`NCT06318364` - Postoperative Delirium in the Post-anesthesia Care Unit
Recruiting	`NCT06318351` - Transcutaneous Acupoint Electrical Stimulation and Postoperative Delirium Delirium
Completed	`NCT01032161` - Perioperative Risk Factors for Postoperative Delirium in Children	N/A
Completed	`NCT05942183` - Optic Nerve Sheath Diameter is Associated With Postoperative Delirium in Patients Undergoing Open Heart Surgery
Not yet recruiting	`NCT06361238` - Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery	Phase 3
Not yet recruiting	`NCT06346990` - The Effect of Listening to Holy Quran Recital on the Incidence of Delirium Post-CABG	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.