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Clinical Trial Summary

To observe the effect of intraoperative dexmedetomidine on the incidence of postoperative delirium, postoperative analgesic drug requirements and pain scores in elderly patients undergoing robot-assisted pancreaticoduodenectomy.


Clinical Trial Description

This study is a multicenter, randomized, double-blind, placebo-controlled trial. Three hundred patients undergoing elective robotic-assisted pancreaticoduodenectomy were randomized to the intervention and control groups. Patients in the intervention group were given a loading dose of 0.6 μg/kg of dexmedetomidine by intravenous infusion within 10 minutes after intubation, followed by a continuous infusion at a rate of 0.4 μg/kg/h until 30 min before the end of the procedure; patients in the control group were given an equal volume of saline. Data were collected at 1-5 days and 1 month postoperative follow-up. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05274789
Study type Interventional
Source Chinese PLA General Hospital
Contact Hao Li, Doctor
Phone 15010665099
Email lihao301@126.com
Status Recruiting
Phase N/A
Start date April 15, 2022
Completion date April 1, 2024

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