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Delirium in Old Age clinical trials

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NCT ID: NCT06326372 Not yet recruiting - Hyperoxia Clinical Trials

The Effect of Intraoperative Hyperoxemia on Postoperative Delirium in Geriatric Patients

Start date: March 20, 2024
Phase:
Study type: Observational

Oxygen therapy is the most common treatment modality for patients with hypoxemia, but target values for normoxemia are not clearly defined. Therefore, iatrogenic hyperoxemia is a very common situation. Even though there are many side effects reported related to hyperoxemia and hyperoxemia is shown to be related to worse outcome than expected; clinicians still observe hyperoxemia frequently. Oxygen reserve index (ORi™) (Masimo Corp., Irvine, USA) can guide clinicians in detection of hyperoxia. ORi is a parameter which can evaluate partial pressure of oxygen (PaO2) rating from 0 to 1. There are growing evidences in ORi that it might be helpful to reduce hyperoxia in general anesthesia. Continuous ORi monitoring can be used for detecting and preventing hyperoxia. The ability to perform FiO2 titration with ORi may be an appropriate monitoring management to prevent the harmful effects of hyperoxia.In this study, in patients who underwent major abdominal surgery; It was aimed to investigate the effectiveness of ORi-guided FiO2 titration in preventing hyperoxia.

NCT ID: NCT06209788 Not yet recruiting - Hip Fractures Clinical Trials

The Efficacy of Music in Preventing Delirium in Elderly Patients With Hip Fracture

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

The aim of this trial is to explore the efficacy of music in preventing delirium in elderly patients with hip fracture. The main aims of this research are: 1. To compare the effectiveness of music intervention in preventing delirium in patients with hip fractures through a randomized controlled trial. The comparisons include respiratory rate, pulse rate, blood pressure, and pain score, as well as the incidence and severity of delirium, opioid analgesic usage, postoperative complications, length of hospital stay, and rates of readmission within 14 days and 30-day mortality. 2. Introduce the evidence-based ''listening music protocol'' in the care of hip fracture patients to prevent delirium, and test the effects through a randomized controlled trial.

NCT ID: NCT06111300 Not yet recruiting - Delirium in Old Age Clinical Trials

Dexmedetomidine Effect on Delirium of Elderly Patients

Start date: November 1, 2023
Phase: Phase 4
Study type: Interventional

The Effect of Dexmedetomidine on the Incidence of Delirium Incidence of Post-operative Delirium in Elderly Patients Undergoing Emergency Laparotomy

NCT ID: NCT05819723 Not yet recruiting - Delirium in Old Age Clinical Trials

Erector Spinae Block and Incidence of Postoperative Delirium After Hip Fracture Surgeries

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

Postoperative pain is a significant risk factor for delirium. This clinical trial will search whether analgesia produced by erector spinae block in elderly patients undergoing hip fracture surgeries reduces delirium or not!

NCT ID: NCT03346226 Not yet recruiting - Delirium in Old Age Clinical Trials

How Different Sedatives Affect Hip Fracture Patient's Postoperative Delirium

Start date: January 1, 2018
Phase: Phase 4
Study type: Interventional

the hypothesis is that Dexmedetomidine seems to decrease incidence of post-operative delirium . one possible mechanism is that Dex have a minor influence on cognition, since it has no effect on GABA receptor,another is that Dex could induce a sleep similar to natural sleep, thereby decreasing sleep deprivation and circadian rhythm disorder in post-operative patients. In this study , investigators devise the two different sedatives(Dexmedetomidine and Propofol)'influence on postoperative delirium in hip fracture elderly participants under spinal anesthesia