Delayed Recovery From Anesthesia Clinical Trial
— MIRCONTROLOfficial title:
Automated Control of End-tidal Volatile Anesthetic Concentration Using the MIRUS System: A Comparison of Isoflurane, Sevoflurane and Desflurane in Anesthesia.
Verified date | January 2015 |
Source | Ruhr University of Bochum |
Contact | n/a |
Is FDA regulated | No |
Health authority | Germany: Ethics Commission |
Study type | Interventional |
The new MIRUS system as well as the established AnaConDa system uses a reflector to conserve volatile anaesthetics (VA). Both systems act with commercially available ICU ventilators. In contrast to AnaConDa the MIRUS includes an automated control of end-tidal VA concentrations. In this study the investigators compared feasibility, costs and recovery times after anaesthesia with isoflurane (ISO), sevoflurane (SEVO) or desflurane (DES) in ventilated and spontaneously breathing patients.
Status | Completed |
Enrollment | 63 |
Est. completion date | December 2014 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Signing of the informed consent document (patient or relatives). - Patient age 18 years or older. - ASA I-III Exclusion Criteria: - ASA IV patients - Epidural or spinal analgesia - Allergy or known hypersensitivity to any of the study drugs - Patients with known or suspected genetic susceptibility to malignant hyperthermia - Previous participation in this trial - Participation in another clinical trial within 4 weeks prior to selection. - Pregnant women |
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Health Services Research
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Ruhr University of Bochum |
Bomberg H, Glas M, Groesdonk VH, Bellgardt M, Schwarz J, Volk T, Meiser A. A novel device for target controlled administration and reflection of desflurane--the Mirus™. Anaesthesia. 2014 Nov;69(11):1241-50. doi: 10.1111/anae.12798. Epub 2014 Jul 9. — View Citation
Meiser A, Sirtl C, Bellgardt M, Lohmann S, Garthoff A, Kaiser J, Hügler P, Laubenthal HJ. Desflurane compared with propofol for postoperative sedation in the intensive care unit. Br J Anaesth. 2003 Mar;90(3):273-80. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | volatile anaesthetics (VA) consumption | duration of anesthesia: max. 3 h | Yes | |
Secondary | recovery times | duration post anesthesia care: max. 8 h after anesthesia | Yes |
Status | Clinical Trial | Phase | |
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Completed |
NCT03614325 -
Virtual Reality in the Operating Room
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N/A |