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Correlation of Molecular Biomarkers With Biopsy Findings and Outcomes in Renal Transplant Recipients

Delayed Graft Function Clinical Trial

Official title:
Correlation of Molecular Biomarkers With Biopsy Findings and Outcomes in Renal Transplant Recipients

Clinical Trial Summary

This is a single-center, prospective, non-randomized, observational study to evaluate specific proteogenomic biomarker panels for acute rejection (AR) and chronic allograft nephropathy/interstitial fibrosis and tubular atrophy (CAN/IFTA) in blood, urine and kidney tissue (biopsy) in kidney transplant recipients. Proteogenomic profiles will be routinely monitored over one year after enrollment.

Clinical Trial Description

OBJECTIVE: The objective of this phase of the study is to allow the clinical site to gain familiarity with patient recruitment, sample and data collection, and interpretation of the proteogenomic biomarker report provided, through retrospective analysis. This phase of the study will provide a platform for the transplant physicians to gain confidence with the format, logistics, and potential use of the biomarker tests on blood and tissue. ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02463253
Study type Observational [Patient Registry]
Source University of California, Davis
Contact
Status Completed
Phase N/A
Start date April 2015
Completion date May 2016
View Details
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