Comparison of Proton Pump Inhibitor and H2 Receptor Blocker on Prevention of Bleeding From Iatrogenic Ulcer After Endoscopic Submucosal Dissection for Gastric Neoplasms: A Prospective Randomized Controlled Trial

Delayed Bleeding Clinical Trial

Official title: Comparison of Proton Pump Inhibitor and H2 Receptor Blocker on Prevention of Bleeding From Iatrogenic Ulcer After Endoscopic Submucosal Dissection for Gastric Neoplasms: A Prospective Randomized Controlled Trial

Status Recruiting

Clinical Trial Summary

after endoscopic submucosal dissection(ESD) of early gastric cancer, conventional proton pump(PPI) inhibitors and H2 receptor antagonists have a controversial effect on preventing bleeding from artificial ulcers. the aim of this study was to investigate whether a stronger acid suppression (high dose PPI) more effectively prevents bleeding after ESD

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Delayed Bleeding
• Hemorrhage
• Stomach Neoplasms

• NCT number: NCT01179724
• Study type: Interventional
• Source: Samsung Medical Center
• Contact: Jae J Kim, professor
• Phone: 82-2-3410-3409
• Email: jjkim@skku.edu
• Status: Recruiting
• Phase: N/A
• Start date: July 2009
• Completion date: September 2010