The Role of Hydration on Exercise Performance - ODIN

Dehydration Clinical Trial

— ODIN  

Official title:

The Role of Hydration on Exercise Performance - ODIN

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02980939
• Other study ID #: 16-10-135
• Status: Completed
• Phase: N/A
• First received: November 30, 2016
• Last updated: May 27, 2017
• Start date: November 2016
• Est. completion date: March 18, 2017

Study information

• Verified date: May 2017
• Source: University of Arkansas, Fayetteville
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

During exercise in the heat, there is a need to replenish fluids in order to avoid dehydration and decrease the risk for heat illness. What drives this urge to drink is the thirst mechanism. Following ingestion of fluids, there is an inhibition of thirst before there is a replenishing of fluids. However, there is little scientific evidence of where thirst is inhibited, if this thirst inhibition is augmented by exercise and how thirst itself influence exercise performance. Further, during rehydration studies, it is very difficult to successfully blind a subject to their drinking/hydration protocol. Previous studies that have blinded a subject to their drinking have used various methods such as intravenous fluid administration and/or nasogastric tubes. Therefore, the purpose of this research is to examine the mechanistic roles thirst inhibition plays while exercising in the heat while undergoing intravenous fluid administration. Specific attention will be directed to the cardiovascular and thermoregulatory function of the individuals. All blood, cardiovascular, thermoregulatory, and perceptual measures are shown in the diagram below.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11
• Est. completion date: March 18, 2017
• Est. primary completion date: March 18, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Cycling Racing History category 3 or higher USA cycling certification

• maximal oxygen uptake >55 ml/kg/min

Exclusion Criteria:

• History of heat stroke

• Renal, cardiovascular, metabolic diseases

• Regular medication

Related Conditions & MeSH terms

• Dehydration

Intervention

Other:
• iv fluid infusion
Intravenous isotonic saline infusion

Locations

Country	Name	City	State
United States	University of Arkansas - HPER	Fayetteville	Arkansas

Sponsors (1)

Lead Sponsor	Collaborator
University of Arkansas, Fayetteville

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	5km - Cycling Time Trial	Time to completion 5 km cycling time trial in the heat	2hour
Secondary	Rectal Temperature	Body core temperature at the end of the 5 km time trial	2hour