Degenerative Spondylolisthesis Clinical Trial
Official title:
Multimodal Perioperative Pain Management of Circumferential Lumbar Fusion Improves Recovery
Convalescence after lumbar fusion is dependent on pain. In orthopaedic and abdominal surgery
accelerated stay programs with optimized pain management enhance recovery.
The objective is to evaluate the effect of a revised and optimized perioperative fast track
program in lumbar fusion surgery.
Major spine surgery is usually associated with high postoperative pain scores and opioid
requirements. Epidural analgesia has been reported to be an effective and safe method to
control postoperative pain after spinal instrumentation surgery, but the overall effects of
pain management on postoperative length of stay and recovery remains debatable.
However, in a multimodal approach, including multimodal non-opioid analgesia to control
postoperative pathophysiology and rehabilitation, complications and hospital stay have been
reduced after arthroscopy, hip arthroplasty and knee arthroplasty, hip fractures and
abdominal surgery and other procedures, when combined with an enhanced recovery program.
The aim of the study is to assess the effect and safety of a combined analgesic regimen
consisting of local anesthetic, intra-operative and post-operative continuous epidural
analgesia and a single dose ketorolac together with a fast track rehabilitation program
after 360 degree lumbar fusion for degenerative disc disease and spondylolisthesis < 2
;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject)
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