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Deep Sedation clinical trials

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NCT ID: NCT06187545 Recruiting - Deep Sedation Clinical Trials

Clinical Performance of the Automated Closed-loop Minimum Viable Prototype

Start date: December 18, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate a minimum viable prototype for automated closed-loop administration of propofol in deep sedated patients under invasive mechanical ventilation in the ICU. The main question it aims to answer is: • whether the minimum viable prototype for automated closed-loop administration of propofol is effective in keeping patients in deep sedation using the lowest possible dose of propofol Participants will undergo deep sedation using the minimum viable prototype for automated closed-loop propofol administration. The usual practice of sedation will be compared with the practice of sedating with the minimum viable prototype to see if the infusion rate of propofol is decreased

NCT ID: NCT05762692 Recruiting - Deep Sedation Clinical Trials

High-flow Nasal Oxygenation During Deep Sedation in Pediatric Dental Patients

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

It is important to choose an appropriate oxygenation technique during intravenous deep sedation in pediatric dental treatment. The study is to evaluate the efficacy and safety of high-flow nasal oxygenation in intravenous deep sedation in pediatric dental patients.

NCT ID: NCT05539521 Recruiting - Critically Ill Clinical Trials

Efficacy and Safety of Remimazolam Besylate Versus Propofol for Sedation in Critically Ill Patients With Deep Sedation

Start date: September 5, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of remimazolam besylate compared to propofol for sedation in critically ill patients with deep sedation.

NCT ID: NCT04842253 Recruiting - Clinical trials for Radiofrequency Ablation

HFNC vs LFNC in Patients With AF Undergoing RFCA Under Deep Sedation.

Start date: January 4, 2022
Phase: N/A
Study type: Interventional

Oxygen supplementation through high flow nasal cannula (HFNC) may reduce the incidence of desaturation and hypoxemia during deep sedation at radiofrequency catheter ablation (RFCA procedures).This study is designed to test the hypothesis that the incidence of hypoxemia and desaturation in patients with atrial fibrillation undergoing RFCA under deep sedation, is less when using HFNC as compared to use of standard low flow nasal cannula (LFNC).

NCT ID: NCT03893877 Recruiting - Deep Sedation Clinical Trials

Comparison of Oxygenation Methods in Sedation

Start date: November 4, 2018
Phase: N/A
Study type: Interventional

Abstract Backgrounds and objectives: Dental treatments, especially in children who can not be cooperated, may require deep sedation due to intense anxiety and fear. During sedation oxygen is usually given to the patients by nasal cannula. Investigators want to use nasal mask for non-invasive mechanical ventilation for oxygenation of the patient during sedation for dental treatment and described it with nasal cannula. Methods: Seventy three children classified as ASA 1 or 2, aged between 3 to 17 will be included for this study. During deep sedation procedure group M will be applied nasal mask in order to noninvazive mechanical ventilation, group C will be applied nasal cannula connected to the oxygen flowmeter.