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Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery — WI223281  

DCIS Clinical Trial

Official title:
Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery

Clinical Trial Summary

This is a feasibility study which will evaluate the effects of pre-operative treatment of DCIS of the breast with palbociclib. Patients with biopsy-proven DCIS are eligible for the study. There will be 2 independent and unrelated study groups of 12 patients each, for a total of 24 patients: 1. Group A, of male or female patients treated with palbociclib single agent (n=12); 2. Group B, untreated, of male or female patients who consented translational studies in blood, as well as diagnostic and definitive surgical specimen, but not the pre-operative treatment with palbociclib (n=12).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Carcinoma, Intraductal, Noninfiltrating
  • DCIS
Clinical Trial Details
NCT number NCT03535506
Study type Interventional
Source Georgetown University
Contact
Status Terminated
Phase Phase 2
Start date October 8, 2018
Completion date December 6, 2023
View Details
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