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Clinical Trial Summary

The aim of this study was to investigate the changes in the scalp lipids and TEWL in dandruff subjects treated by 1% Selenium Disulfide (SeS2)/1% salicylic acid-based shampoo after an antidandruff treatment and after a remanence phase


Clinical Trial Description

Dandruf often has a substantial negative impact on quality of life. The proliferation of Malassezia specie has been shown to be linked to dandruff. Yet, the sebum is essential for the growth of Malassezia restricta. The sebum is mainly constituted by waxes, squalene and triglycerides. The triglycerides are partially transformed in free fatty acids while the squalene can be oxidized. Therefore, the change in lipids can be of interest for dandruff studies. The scalp barrier function of a dandruff scalp is known to be altered and must recover after an antidandruff treatment The aim of this study is to investigate the change of the scalp lipids and TEWL after a 1% selenium disulfide and 1% salicylic acid antidandruff shampoo on dandruff scalp and after a remanence period ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05503706
Study type Interventional
Source L'Oreal
Contact Philippe MASSIOT, pHD
Phone 0660992467
Email philippe.massiot@rd.loreal.com
Status Not yet recruiting
Phase N/A
Start date September 2022
Completion date December 2022

See also
  Status Clinical Trial Phase
Not yet recruiting NCT05506592 - Evaluation of the Efficacy of SeS2 Shampoo on Subjects Having Dandruff N/A
Completed NCT02448082 - The Efficacy of Sodium Shale Oil Sulponate 1% Shampoo in the Treatment of Pityriasis Capitis Phase 2
Completed NCT06436495 - Methodology Validation: Correlating Adherent Scalp Flaking Score (ASFS) With Phototrichogram for Scalp Dandruff Evaluation in Adult Subjects N/A
Recruiting NCT05319444 - Cleansing Device for the Treatment of Scalp and Hair Conditions N/A
Completed NCT05989633 - DERCOS DS DANDRUFF TREATMENT OBSERVATIONAL STUDY 2022
Completed NCT06052241 - Artificial Intelligence-based Prescription of Personalized Scalp Cosmetics N/A